Taking Action to Combat Coronavirus 2's Severe Acute Respiratory Syndrome Challenges (SARS-Cov-2)
Received: 03-Feb-2023 / Manuscript No. Jidp-23-89059(PQ) / Editor assigned: 06-Feb-2023 / PreQC No. Jidp-23-89059(PQ) / Reviewed: 20-Feb-2023 / QC No. Jidp-23-89059 / Revised: 22-Feb-2023 / Manuscript No. Jidp-23-89059(R) / Published Date: 28-Feb-2023 QI No. / Jidp-23-89059
Abstract
Clinical molecular laboratory professionals are at the frontline of the response to the severe acute respiratory pattern coronavirus 2 (SARS- CoV- 2) epidemics, furnishing accurate, high- quality laboratory results to prop in opinion, treatment, and epidemiology. In this part, we've encountered multitudinous nonsupervisory, payment, forcechain, logistical, and systems challenges that we've plodded to overcome to fulfil our calling to give patient care. In this Perspective from the Association for Molecular Pathology Infectious Disease Subdivision Leadership platoon, we review how our members have risen to these challenges, give recommendations for managing the current epidemic, and outline the way we can take as a community to more prepare for unborn afflictions. There are numerous factors as to why the response to severe acute respiratory pattern coronavirus 2( SARS- CoV- 2) in the United States has been different from former epidemic responses, and the thing herein is to validate challenges to the SARS- CoV- 2 response and give original recommendations to more prepare for the coming epidemic. In 2009, the influenza A H1N1 epidemic was the first epidemic in the age of molecular diagnostics. The large network of academic and community sanitarium laboratories throughout the United States was suitable to develop and validate molecular tests in the first week of the outbreak to rule out H1N1 as the cause of a case's illness, and this played a critical part in containing the H1N1 epidemic. For illustration, in Chicago, IL, during the first month of the epidemic, 62 of the cases screened for H1N1 influenza were tested by community molecular diagnostics laboratories, with a typical reversal time of 24 hours. The clinical laboratory community fleetly handed extensively available H1N1 influenza molecular testing, easing a nippy epidemic response.
Keywords
SARS; MERS; Influenza; Legionella; Pathology
Introduction
These conditioning are within the compass of practice for our molecular individual professionals. Involvement of the meetly good molecular laboratory professional in every aspect of furnishing critical individual testing services during the response to an arising pathogen mitigates pitfalls and promotes patient safety. Important of the arising published work on the development of new clinical tests for SARS- CoV- 2 represents moxie and work arising from university medical center and sanitarium- grounded laboratories. This isn't to neglect the impact of innovative testing developed in marketable referral laboratories, as well as the considerable impact of marketable development of new testing platforms [1, 2]. Referral laboratories play an important part in the development and performance of tests for contagious conditions, furnishing critical access to testing for community and lower hospitals. Wide vacuity of laboratory- developed and marketable assays can help accelerate provision of community- grounded clinical laboratory testing, eventually shortening test affect reversal time and permitting rapid-fire identification of and public health intervention with infected individualities. It's vital to have all stakeholders in the clinical laboratory community induce further openings for invention in the design of new COVID- 19 tests and testing strategies. In addition, public health laboratories play a critical part through contact dogging, epidemiologic data operation and analysis, outbreak constraint, and information dispersion to help check the spread of infection. Eventually, the success of the SARS- CoV- 2 epidemic testing response requires ALL of us [3, 4].
Materials and Method
Recommendations for managing the current pandemic
The Association for Molecular Pathology( AMP) contagious conditions Subdivision Leadership is apprehensive of and involved in multiple sweats to address SARS- CoV- 2 testing development, test quality and interpretation, operation, and limited resource operation. During the epidemic, guidance from AMP subject matter experts will continue to be handed in multiple formats. The authors anticipate furnishing fresh dispatches as demanded to validate and to address arising challenges. Throughout the course of the SARS- CoV- 2 response, the AMP has continually maintained a website curating COVID- 19 – affiliated scientific, nonsupervisory, and payment coffers last penetrated April 28, 2020). On February 20 and May 14, the AMP handed freely accessible online education regarding the COVID- 19 epidemic last penetrated May 5, 2020; and last penetrated May 27, 2020); fresh webinars will give periodic updates [5, 6]. The AMP has conducted a robust COVID- 19 testing check designed to identify and understand the laboratory community's challenges, with original data from over 100 US- grounded laboratories available, last penetrated May 28, 2020). AMP member peer- to- peer listserv dispatches have been robust as associates fleetly participated enterprises, challenges, knowledge, experience, and results to support the clinical laboratory community's COVID- 19 testing response. Multiple AMP subject matter experts have been featured in media interviews and are interacting on social media outlets, effectively communicating laboratory community enterprises and pressing multitudinous success stories in malignancy of grueling conditions last penetrated April 28, 2020). We hail the sweats of AMP members from each over the world, other professional societies, and laboratory professionals around the world for their leadership and fidelity to patient care during this time of rapid-fire change and insecurity [7, 8].
Conclusion
Clinical laboratory croakers and professionals are in the vanguard of the response to the SARS- CoV- 2 epidemic, furnishing accurate, high- quality laboratory results to prop in opinion, treatment, and epidemiology. In this part, we've encountered multitudinous nonsupervisory, payment, force- chain, logistical, and systems problems that we've plodded to overcome to fulfill our calling to give patient care. Despite the challenges and lapses, the skeleton of largely trained and devoted molecular individual professionals of the AMP has risen to the challenge and is furnishing the vital individual intelligence demanded for effective operation of this epidemic. Although the current successes were achieved through determination and imagination, our gests suggest that the hurdles and obstacles that have been encountered weren't ineluctable and clearly bloodied our public recognition of and response to the epidemic. To prepare for the coming unanticipated challenges, thoughtful reconsideration and intervention into crucial areas will ameliorate our capability to watch for cases and society when the coming extremity arises.
On behalf of AMP, we fete and thank our members and all members of the multidisciplinary medical brigades for their moxie, fidelity, and service. Organizationally, AMP will continue to proactively give critical information and coffers in support of all laboratory professionals involved in COVID- 19 response conditioning. We'll also continue to engage in, encourage, and support collaboration between all stakeholders to overcome SARS- CoV- 2 and continue to put the care of cases first, every day [9, 10].
Acknowledgement
We thank Daniel N. Cohen (Association for Molecular Pathology (AMP) Infectious Disease Subdivision member); Eric Konnick and Jordan Laser (AMP Professional Relations Committee); AndrésG. Madrigal (AMP Clinical Practice Committee inferior member); and Robyn Temple-Smoking and Tara Burke (AMP)
Conflict of Interest
None
References
- Wakako F, Andrea M (2019) Ebola Virus: Pathogenesis and Countermeasure Development. Annu Rev Virol 29: 435- 458.
- Edward CH, Gytis D, Andrew R, Kristian GA (2016) The evolution of Ebola virus: Insights from the 2013-2016 epidemic. Nature 538: 193-200.
- Dolzhikova IV, Shcherbinin DN, Logunov DY, Gintsburg AL (2021) [Ebola virus ( Filoviridae: Ebolavirus: Zaire ebolavirus): fatal adaptation mutations]. Vopr Virusol 66: 7-16.
- Marissa B, Mbuso F, Mahmoud ESS (2017) Ebola virus: A gap in drug design and discovery - experimental and computational perspective. Chem Biol Drug Des 89: 297-308.
- Thomas H, Allison G, Heinz F (2019) Therapeutic strategies to target the Ebola virus life cycle. Nat Rev Microbiol 17: 593-606.
- Hatem AE, Timothy BE, Bellur SP (2015) Ebola virus outbreak, updates on current therapeutic strategies. Rev Med Virol 25: 241-253.
- Saskia DB, Barbara JM, Tolbert GN, Amara J, Moumie B, et al. (2019) Ebola Virus Infection Associated with Transmission from Survivors. merg Infect Dis 25: 249-255.
- Sizikova TE, Lebedev VN, Borisevich SV (2019) [Virus specific antibody - based remedies for the urgent prevention and treatment of Ebola virus disease]. Ter Arkh 91: 98-104.
- Elisa F, Aldo F, Angela C, Enzo T (2019) Insights into Ebola Virus VP35 and VP24 Interferon Inhibitory Functions and their Initial Exploitation as Drug Targets. Infect Disord Drug Targets 19: 362-374.
- Olivier G (2017) Olivier G (2017) Use of convalescent plasma in Ebola virus infection. Transfus Apher Sci 56: 31-34.
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Citation: Lu LL (2023) Taking Action to Combat Coronavirus 2's Severe Acute Respiratory Syndrome Challenges (SARS-Cov-2). J Infect Pathol, 6: 175.
Copyright: © 2023 Lu LL. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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