Possibilities of Surgical Interventions in Severe Lower Limb Ischemia in the Stage of Trophic Disorders
Received: 01-May-2023 / Manuscript No. jmis-23-97273 / Editor assigned: 04-May-2023 / PreQC No. jmis-23-97273 / Reviewed: 18-May-2023 / QC No. jmis-23-97273 / Revised: 22-May-2023 / Manuscript No. jmis-23-97273 / Published Date: 29-May-2023 DOI: 10.4172/jmis.1000172
Abstract
Critical lower limb ischemia with the stages of trophic disorders is the end stage condition of lower extremities. Mostly expedites to disability of the lower limb and unfavorable prognosis in terms of affected limb preservation and mortality. Occlusive pathology in the branches of aortic bifurcation remains an urgent task of endovascular surgery in all highly developed countries throughout the world. Simultaneously, often the pathology is characterized by the atherosclerotic etiology of unilateral or bilateral lesions of the iliac arteries. Critical ischemia of the lower extremities affects about 1% of men over 55 years of age. First line diagnosis of Peripheral arterial disease is Ankle-Brachial Index (ABI). In modern times, for the diagnosis of patients with severe limb threatening ischemia, R.Fontine and WIFI (Wound Ischemia Foot Infection) classifications have been used to assess the severity of the patients (Table 1).
Keywords
Cross shunting; Surgical revascularization; Autologous allograft; Athero-diabetic occlusion; Severe limb ischemia
Introduction
Resection with prosthetics or Aorto-femoral bypass provide an adequate result in such clinical observations and generally stands as the only considerable method of management. These days, most of the endovascular surgeons prefer to perform reconstructive surgeries of iliac arteries, especially in case of distal ischemic purulent-necrotic conditions. In cross-shunting operations the “Crossover” technique has been proven to be a gentler and appropriate aspect of surgery in the treatment of unilateral pathological processes [1].
In the correction of infrainguinal occlusions of the vascular bed of lower extremities in case of atherosclerotic lesions of the arterial pathways, Angioplasty has been the ideal choice of surgical interventions. At the same time, only half of them can perform revascularization surgery. Without surgery, 40% of patients undergo amputation of the lower limb within 6 months after diagnosis, 20% of patients die. To minimalize the catastrophic outcomes of reconstructive surgery of the arteries the following methods which have showed promising results are, the use of modern explants with high rheological properties, the use of autologous shunting material, especially with minimal disintegration and traumatization of the endothelium, implantation of allografts with elements of transplantation techniques [2].
Goals of the study: In order to determine the optimal approach of treatment for the elimination of severe ischemia, especially in the presence of clinically significant trophic disorders, the results of various modern reconstructive techniques used in ilio-femoral-popliteal occlusive lesions of the arteries in the lower extremities were evaluated among patients.
Materials and Methods
Department of Surgical Diseases-I of Grodno University Clinic within the last two years performed, restoration and reconstruction of arterial blood flow in the aorto-femoral segment in 12 patients with gangrenous-ischemic limb trophic disorders categorized as staged IIIIV according to the R.Fontine - A.V.Pokrovsky staging.
During the same period, femoral-popliteal-tibial arterial reconstructions were performed, 56 operated patients with a similar nature of tissue damage. In 50 patients, the occlusive process had an atherosclerotic etiology, and in 18 cases, ischemia was due to atherodiabetic lesions. The age of the patients ranged from 59 to 78 years old, among the operated there were 13 women and 45 men [3, 4].
Results and Discussion
As per the analysis obtained through the above discussed study it was revealed that the choice of the reconstructive methods depends on the patient’s individual conditions. Primarily determined by the presence of an adequate main subcutaneous autogenous vessel, the state of the distal vascular bed during operations below the inguinal ligament, the degree and prevalence of necrotic ischemic tissue damage and somatic status of the patient played a major role in choosing the surgical option in the aorto-ilio-femoral segment [5].
Aorto-femoral bypass operations were performed in 5 patients with occluded aorto-iliac segment and necrotic lesions without perifocal inflammation patients at bifurcation - and 3 patients in linear. In the other 5 patients, prolonged unilateral or segmental obstruction of the aorto-ilio-femoral segment was removed by the original surgical technique of multifocal tunnel de-obliteration. The method of more gentle cross-shunting operations of the “crossover” type turned out to be an expedient and preferred option for choosing surgical treatment for unilateral pathological processes in this segment in 2 patients with a pronounced comorbid status [6, 7].
From the infra-inguinally operated patients with the help of autologous vascular structures, 22 had femoral-popliteal bypass surgery with a reversed vein below the knee joint gap; similar bypass surgery was performed proximally in 8 cases. In 11 patients operated with extended occlusions of the superficial femoral and popliteal arteries, distal anastomosis was super imposed with the tibial arteries below the level of distal obstruction. The restoration of the main blood flow in the popliteal and tibial arteries according to the “in situ” method was carried out in 14 people. In the 1st clinical observation, with the repeated nature of surgical intervention and in the absence of autologous material during bypass surgery in the femoral-popliteal position, an arterial allograft with elements of graft technology was successfully transplanted [8, 9].
Components | Score | Description | ||
---|---|---|---|---|
0 | No ulcer (ischemic rest pain) | |||
1 | Small, shallow ulcer on distal leg or foot without gangrene | |||
W(Wound) | 2 | Deeper ulcer with exposed bone, joint or tendon with/without extensive gangrene | ||
3 | Extensive deep ulcer, full thickness heel ulcer with/without calcaneal involvement with/without extensive gangrene | |||
ABI | Ankle pressure (mmHg) | Toe pressure or TcPO2 | ||
0 | ≥0.80 | >100 | ≥60 | |
I(Ischemia) | 1 | 0.60-0.79 | 70-100 | 40-59 |
2 | 0.40-0.59 | 50-70 | 30-39 | |
3 | <0.40 | <50 | <30 | |
0 | No symptoms / signs of infection | |||
1 | Local infection involving only skin and subcutaneous tissue | |||
FI(foot infection) | 2 | Local infection involving deeper than skin /subcutaneous tissue | ||
3 | Systemic inflammatory response syndrome |
In the early postoperative period, 5 of the operated patients developed complications that required repeated surgical interventions the 1st - bleeding from the anastomosis, in the 4th-thrombosis. In 2 patients, adequate revascularization of the limb was not achieved and amputation was performed. A limb with positive dynamics in a functional state was preserved in 97.1% [10-12].
Conclusion
Hence, with regards to aforementioned validation of the study, the use of autogenous venous material, modern original de-obliterating reconstructions of arterial vasculature and transplantable allograft structures may be promising in the amelioration of occlusive pathology in severe life threatening lower limb ischemia in the stage of trophic disorders.
Conflict of Interest
None
Acknowledgement
None
References
- Russu E, Mureșan V, Arbănași EM, Kaller R, Hosu I, et al. (2022) The Predictive Role of NLR and PLR in Outcome and Patency of Lower Limb Revascularization in Patients with Femoropopliteal Disease.J Clin Med. 11: 26-30.
- Muresan, Cosarca VA, Russu MC, Niculescu E, Soimu R, et al.(2021) An Alternative Treatment Strategy to Critical Limb Ischemia (CLI) J Interdiscip Med 6: 108–111.
- Russu, Eliza, Adrian Vasile Mureșan, Daniela Elena Nedelea, Raluca Niculescu, et al. (2023) Polytetrafluorethylene (PTFE) vs. Polyester (Dacron) Grafts in Critical Limb Ischemia Salvage.Int J Environ Res Public Health20: 212-220.
- Shu J, Santulli G (2018) Update on peripheral artery disease: Epidemiology and evidence-based facts. Atherosclerosis. 275: 379-381.
- Conte MS, Bradbury AW, Kolh P, White JV, Dick F, et al.(2019) Global vascular guidelines on the management of chronic limb-threatening ischemia. J Vasc Surg 69: 3-125.
- Panigada M, Bottino N, Tagliabue P (2020) Hypercoagulability of COVID-19 patients in intensive care unit: a report of thromboelastography findings and other parameters of hemostasis. J Thromb 18: 1738-1742.
- Giannis D, Ziogas IA, Gianni P (2020) Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past. J Clin Virol 127: 104-105.
- Harrison SL, Fazio-Eynullayeva E, Lane DA, Underhill P, Lip GYH (2020) Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: a federated electronic medical record analysis. PLoS Medicine 17-106-109.
- Dye TD, Bogale S, Hobden C, Tilahun Y, Deressa T, et al. (2011) Experience of Initial Symptoms of Breast Cancer and Triggers for Action in Ethiopia. Int J Cancer 5: 2012-2015.
- Anderson BO, Shyyan R, Eniu A, Smith R, Yip CH, et al. (2006) Breast cancer in limited-resource countries an overview of the Breast Health Global Initiative 2005 guidelines. Breast J 12: 12-15.
- Chow, Loh, Wong, Cheng, Fung, et al. (2007) Using a community-based outreach program to improve breast health awareness among women in Hong Kong. Public Health Nurs 24: 125-128.
- Bener, Ayoubi, Moore, Basha, Joseph, et al. (2009) Do we need to maximize breast cancer screening awareness Experience with an endogamous society with high fertility. Asian Pac J Cancer 10: 599-604.
Google Scholar, Crossref, Indexed at
Google Scholar, Crossref, Indexed at
Google Scholar, Crossref, Indexed at
Google Scholar, Crossref, Indexed at
Google Scholar, Crossref, Indexed at
Google Scholar, Crossref, Indexed at
Google Scholar, Crossref, Indexed at
Google Scholar, Crossref, Indexed at
Google Scholar, Crossref, Indexed at
Google Scholar, Crossref, Indexed at
Google Scholar, Crossref, Indexed at
Citation: Jafir JAM (2023) Possibilities of Surgical Interventions in Severe Lower Limb Ischemia in the Stage of Trophic Disorders. J Med Imp Surg 8: 172. DOI: 10.4172/jmis.1000172
Copyright: © 2023 Jafir JAM. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Share This Article
Recommended Conferences
42nd Global Conference on Nursing Care & Patient Safety
Toronto, CanadaRecommended Journals
Open Access Journals
Article Tools
Article Usage
- Total views: 712
- [From(publication date): 0-2023 - Dec 25, 2024]
- Breakdown by view type
- HTML page views: 636
- PDF downloads: 76