ISSN: 2572-4983

Neonatal and Pediatric Medicine
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Book Review   
  • Neonat Pediatr Med 2022, Vol 8(7): 251
  • DOI: 10.4172/2572-4983.1000251

Neonatal Mast Cells and Transplacental Ige Transfer

Dominic Alex*
Assistant Clinical Professor of Paediatric, Loma Medical University, Bristol, United Kingdom
*Corresponding Author: Dominic Alex, Assistant Clinical Professor of Pediatric, Linda Medical University, Bristol, United Kingdom, Email: doalex@gmail.com

Received: 02-Jul-2022 / Manuscript No. nnp-22-69979 / Editor assigned: 04-Jul-2022 / PreQC No. nnp-22-69979 / Reviewed: 18-Jul-2022 / QC No. nnp-22-69979 / Revised: 22-Jul-2022 / Manuscript No. nnp-22-69979 / Published Date: 29-Jul-2022 DOI: 10.4172/2572-4983.1000251

Abstract

Atopic diseases, including food allergy, allergic rhinitis, atopic dermatitis, and asthma, exhibit some degree of heritability. Although large cohort studies suggest that this heritability emerges at least in part from the interaction of genetic, epigenetic, and environmental conditions

Keywords

Immuno; Infection; Vaccine; Body

Introduction

The immune system is the body’s defence mechanism, protecting against invaders like bacteria and viruses to keep us healthy.Cells are the main building blocks of our body. Our immune system relies on many different types of cells, each playing an important role [1-3]. Many of these can be found in our bloodstream, especially white blood cells, which are the main component of the human immune system.White blood cells are strategically located throughout the body, not only in the bloodstream but in the lymph nodes, spleen, lungs, intestines and skin. This allows them to deal with pathogens wherever they enter the body.There are two main types of white blood cells: guardian cells responsible for innate immunity (your body’s first defence against pathogens) lymphocytes responsible for specific or ‘adaptive’ immunity (your body’s ability to remember pathogens and react quickly if reinfected) [4-5].Other blood cell types include red blood cells, which carry oxygen to our tissues, and platelets, which help our blood to clot. Innate immunity The skin and the lining of the lungs and intestine are the first line of defence against infection, forming a physical barrier for protection [6]. These tissues and the sentinal cells that live there form the innate immune system There are two types of lymphocytes: T cells and B cells. T cells respond to infections by releasing chemicals called cytokines, which trigger protective inflammation. T cells can also kill cells that have a pathogen, such as a virus, hidden inside them B cells, often with help from T cells, are involved in making antibodies. Antibodies are complex proteins that attach in a ‘lock-and-key’ fashion either to pathogens or to the toxins released by them.

Conclusion

In conclusion, definitively established that both IgG and IgE are capable of crossing the maternal-fetal interface via FcRN and that the IgE that passes to the fetus in this manner can be bound by MCs in both mice and humans. From an evolutionary perspective, maternal transmission of IgE may have evolved to help protect newborn mammals from xenobiotic venoms and ectoparasites. Although this study illustrates the potential for antigen-specific transfer of IgE sensitization, further focused studies will be required to determine whether such transfer contributes to atopic disease susceptibility and development in humans.

References

  1. Shahapure S (2018) A Study On Parent’s Opinion Towards Swarna Bindu Prashana In Kalaburagi City. IJPERA 3(2):01-04.
  2. Google Scholar

  3. Rao NP, Shailaja U, Mallika KJ, Desai SS, Debnath P (2012) Traditional Use Of Swarnamrita Prashana As A Preventive Measure: Evidence Based Observational Study In Children. IJRiAP 3(5):1-5.
  4. Indexed at, Google Scholar, Crossref

  5. Aniket P, Pallavi D, Aziz A, Avinash K, Vikas S (2017) Clinical effect of suvarna bindu prashan. JAIMS 2(3):11-8.
  6. Indexed at, Google Scholar

  7. Gaikwad A (2011) A Comparative pharmaco-clinical study of Madhu-Ghrita and SwarnaVacha Madhu-Ghrita on neonates. Ayurved MD Research thesis. Jamnagar IPG T & R. A Gujarat Ayurveda University.
  8. Indexed at, Google Scholar, Crossref

  9. Parotto M, Cooper RM, Behringer EC (2020) Extubation of the Challenging or Difficult Airway. Curr Anesthesiol Rep 4: 1-7.
  10. Indexed at, Google Scholar, Crossref

  11. Patel MR, Piazza CC, Martinez CJ, Volkert VM, Christine MS (2002)An evaluation of two differential reinforcement procedures with escape extinction to treat food refusal.J Appl Behav Anal 35: 363-374.
  12. Indexed at, Google Scholar, Crossref

  13. Bernard-Bonnin AC (2006)Feeding problems of infants and toddlers. Can Fam Physician 52: 1247-1251.
  14. Indexed at, Google Scholar

  15. Davies WH, Satter E, Berlin KS (2006)Reconceptualizing feeding and feeding disorders in interpersonal context: the case for a relational disorder.J Fam Psychol 20: 409-417.
  16. Indexed at, Google Scholar

  17. Poppert KM, Patton SR, Borner KB (2015)Systematic review: mealtime behavior measures used in pediatric chronic illness populations.J Pediatr Psychol 40: 475-486.
  18. Indexed at, Google Scholar, Crossref

Citation: Alex D (2022) Neonatal Mast Cells and Transplacental Ige Transfer. Neonat Pediatr Med 8: 251. DOI: 10.4172/2572-4983.1000251

Copyright: © 2022 Alex D. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Post Your Comment Citation
Share This Article
Recommended Conferences
Article Usage
  • Total views: 1627
  • [From(publication date): 0-2022 - Nov 21, 2024]
  • Breakdown by view type
  • HTML page views: 1440
  • PDF downloads: 187
Top