Mechanical properties of biomaterials
Abstract
Materials that are utilized for biomedical or clinical applications are known as biomaterials. The following articledeals with 5th generation biomaterials that are utilized for bone structure replacement. For any fabric to be categorised for biomedical application three requirements must be met. The 1st requirement is that the fabric mustbe biocompatible; it intends that the organism should not treat it as a foreign object. Secondly, the fabric should be biodegradable (for in-graft only); the fabric should harmlessly degrade or dissolve in the body of the organism to permit it to renew commonplace functioning. Thirdly, the fabric should be mechanically sound; for the replacement of load bearing structures, the fabric should possess the same as or better mechanical stability to make sure elevated reliability of the graft.
Introduction
Elastic modulus is simply defined as the ratio of emphasise to strain within the proportional limit. Physically, it serves the stiffness of a fabric within the elastic range when tensile or compressive load are applied. It's clinically necessary because it denotes the choosen biomaterial has lookalike deformable properties with the fabric It's going to replace. These force-bearing materials need soaring elastic modulus with low deflection. As the elastic modulus of fabric increases break resistance decreases. It's super that the biomaterial elastic modulus is lookalike to bone. This is because if It's over bone elastic modulus then load is born by fabric only; while the load is tolerate by bone only if It's less than bone material [1].
The Elastic modulus of a fabric is overall calculated by bending test because deflection can be easily measured in this case as compared to extremely limited elongation in compressive or tensile load. However, biomaterials (for bone replacement) are normally porous and the sizes of the samples are small. Therefore, nanoindentation test is utilized to decide the elastic modulus of these materials. This technique has tall precision and handy for micro scale samples. Howsoever technique of elastic modulus measurement is non-destructive method. It's additionally clinically extremely excellent process due to its simplicity and repeatability since materials are not destroyed [2].
Hardness
Hardness is a degree of plastic deformation and is defined as the force per unit place of indentation or penetration. Hardness is one of the the vast majority of necessary parameters for comparing properties of materials. It's utilized for finding the suitability of the clinical use of biomaterials. Biomaterial hardness is super as equal to bone hardness. If higher than the biomaterial, then it penetrates in the bone. Higher hardness results in less abrasion. As overhead said, biomaterials sample are extremely little therefore, micro and nano scale hardness test (Diamond Knoop and Vickers indenters) are used[3].
Fracture strength
Strength of materials is defined as the greatest emphasise that can be endured before break occurs. energy of biomaterials (bioceramics) is an necessary mechanical property because they're brittle. In breakable materials love bioceramics, cracks easily fecundate when the fabric is subject to tensile loading, in contrast with compressive loading. there are numerous methods are accessible for determining the tensile vigor of materials, for example the bending flexural test, the biaxial flexural force test and the weibull approach. In bioceramics, flaws influence the reliability and potency of the fabric during implantation and fabrication. There're a lot of there are numerous ways that flaws can be generated in bioceramics for example thermal sintering and heating. The importance is for bioceramics to have tall reliability, instead of elevated strength.
The potency of breakable materials depends on the size of flaws distributed all over the material. According to Griffith’s theory of break in tension, the greatest flaw or crack will play a role the the vast majority of to the failure of a material. muscle additionally depends on the volume of a specimen since flaw size is restricted to the size of the specimen’s cross-section. Therefore, the smaller the specimen (e.g., fibers), the higher the break strength. Porosity of implanted bio ceramic has a titanic influence on the physical properties. Pores are normally formed during processing of materials. Increasing the porosity and pore size intends increasing the relative void volume and decreasing density; this leads to a reduction in mechanical properties and lowers the in general might of bioceramic [4].
To use ceramics as self-standing implants that are adept to resist tensile emphasise is a most important engineering construct objective. Four general approaches have been utilized in order to get this objective: 1) use of the bioactive ceramic as a coating on a metal or ceramic substrate 2)strengthening of the ceramic, that is via crystallization of glass 3) use of break mechanics as a construct advance and 4) reinforcing of the ceramic with a moment phase.
For example, hydroxyapatite and other calcium phosphates bioceramics are necessary for tough tissue repair due to their similarity to the minerals in commonplace bone, and their perfect biocompatibility and bioactivity but they have unpleasant Tire resistance and strength. Hence, bioinert ceramic oxides having lofty power are utilized to improve the densification and the mechanical properties of them [5].
Fracture toughness
Fracture toughness is needd to change the crack propagation in ceramics. It's expedient to assess the serviceability, performance and lengthy term clinical success of biomaterials. It's reported that the lofty break toughness fabric enhaced clinical performance and reliability as compared to to low break toughness.[4] It can be measured by various methods e.g. indentation fracture, indentation strength, single edge notched beam, single edge pre cracked beam and double cantilever beam
Fatigue
Fatigue is defined as failure of a fabric due to repeated/cyclic loading or unloading (tensile or compressive stresses). It's additionally an necessary parameter for biomaterial because cyclic load is applied during their representing life. In this cyclic loading condition, micro crack/flaws may be produced at the interface of the matrix and the filler. This micro crack can commence permanent plastic deformation which results in immense crack propagation or failure. During the cyclic load various factor additionally play a role to microcrack generation for example frictional sliding of the mating surface, progressive wear, residual emphasise at grain boundaries, emphasise due to shear[6]
References
- Katti, KS (2004). Biomaterials in total joint replacement. Colloids and Surfaces B Biointerfaces 39: 133-142.
- Wang RZ, Cui FZ, Lu HB, Wen HB, et al. (1995) Synthesis of nanophase hydroxyapatite/collagen composite. J mater sci let 14: 490-492.
- Kokubo, T. (Ed.). (2008). Bioceramics and their clinical applications. Woodhead Pub. and Maney Pub.
- Fischer H, Marx R (2002). Fracture toughness of dental ceramics: comparison of bending and indentation method. Dental Mater 18: 12-19.
- Chen Q, Zhu C, Thouas GA (2012 Progress and challenges in biomaterials used for bone tissue engineering: bioactive glasses and elastomeric composites. Progress in Biomaterials 1:1-22.
- Amaral M, Lopes MA, Silva RF, Santos JD (2002) Densification route and mechanical properties of Si 3 N 4–bioglass biocomposites. Biomater 23: 857-862
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