Journal of Biotechnology & Biomaterials
Open Access

Biofilm bioreactors; Biotechnology; Microbial processes; Planktonic cultures

Introduction

Traditional bioreactors, relying on planktonic cultures, have long been the workhorses of industrial microbiology. However, the limitations inherent in these systems, including lower cell densities and susceptibility to environmental fluctuations, have prompted the exploration of alternative strategies. Enter biofilm bioreactors, designed to capitalize on the natural tendency of microorganisms to form structured communities attached to surfaces [1,2].

Enhanced productivity

The transition to biofilm-based systems heralds a new era of enhanced productivity in biotechnological processes. By fostering the formation of dense microbial communities, biofilm bioreactors allow for higher cell densities and metabolic activities. This translates into increased yields and more efficient utilization of resources, addressing a critical need for sustainability in various applications [3,4].

Improved resistance to environmental stressors

The inherent structure of biofilms provides a shield against environmental stressors. Microbial communities within biofilms exhibit increased resilience, making them well-suited for applications where robust microbial activity is essential. This resistance to fluctuations in nutrient availability and other operational parameters contributes to the reliability and stability of biofilm bioreactors [5].

Diverse applications in biotechnology

The impact of biofilm bioreactors spans a multitude of biotechnological applications. From wastewater treatment and bioremediation to bioenergy production, pharmaceutical applications, and beyond, the versatility of biofilm-based systems is reshaping the landscape of biotechnological innovation [6,7].

Sustainability in agriculture

In the realm of agricultural biotechnology, biofilm bioreactors offer sustainable solutions. These systems contribute to the development of microbial formulations for soil enrichment, plant growth promotion, and the biocontrol of plant pathogens. The controlled release of beneficial microorganisms from biofilms aligns with the principles of environmentally friendly and economically viable agricultural practices [8].

Scalability and cost efficiency

Biofilm bioreactors, with their compact design and scalability, present an attractive proposition for industrial applications. The ability to cultivate robust microbial communities in a space-efficient manner contributes to cost efficiency, a crucial factor in large-scale production processes [9,10].

Conclusion

In conclusion, the impact of biofilm bioreactors in biotechnology is profound, offering solutions to challenges across multiple domains. From wastewater treatment to bioenergy production and pharmaceutical applications, the unique characteristics of biofilmbased systems are shaping a sustainable and efficient future for biotechnological processes. This abstract provides a glimpse into the diverse applications where biofilm bioreactors are driving innovation and advancing the field of biotechnology.

1. Warnock JN, Al-Rubeai M (2006). Bioreactor systems for the production of biopharmaceuticals from animal cells. Biotechnol Appl Biochem 45:1-12.

Indexed at, Google Scholar, Crossref

2. Harding MW, Marques LLR, Howard RJ (2009). Can filamentous fungi form biofilms? Trends Microbiol. 17: 475-480.

Indexed at, Google Scholar, Crossref

3. Fukuda H (1995). Immobilized microorganism bioreactors. In Asenjo JA, Merchuk JC. Bioreactor system design. Marcel Dekker Inc, New York. 339-375.

Google Scholar

4. Gross R, Schmid A, Buehler K (2012).Catalytic biofilms: a powerful concept for future bioprocesses. In: Lear G, Lewis GD (eds) Microbial biofilms. 193-222.
5. Kobayashi M, Shimizu S (2000). Nitrile hydrolases. Curr Opin Chem Biol. 4: 95-102.

Indexed at, Google Scholar, Crossref

6. Murphy CD (2012). The microbial cell factory. Org Biomol Chem. 10:1949-1957.

Indexed at, Google Scholar, Crossref

7. Crueger W, Crueger A, Brock TD (1990). Biotechnology. A textbook of industrial microbiology, 2nd edn. Sinauer Associates, Sunderland.

Google Scholar

8. Kersters K, Lisdiyanti P, Komagata K (2006). The family Acetobacteracea: the genera Acetobacter, Acidomonas, Asaia, Gluconacetobacter, Gluconobacter, and Kozakia. In: Dworkin M (ed) Prokaryotes, vol 5. Springer Science? Business Media, New York.163-200.

Google Scholar

9. Li XZ, Hauer B, Rosche B (2007). Single-species microbial biofilm screening for industrial applications. Appl Microbiol Biotechnol. 76:1255-1262.

Indexed at, Google Scholar, Crossref

10. Cronenberg CCH, Ottengraf SPP, Vandenheuvel JC (1994). Influence of age and structure of penicillium chrysogenum pellets on the internal concentration profiles. Bioprocess Eng. 10: 209-216.

Google Scholar