Effects of Low-Carbohydrate Diet Therapies on Metabolic Control in Type 2 Diabetics as Compared to Low-Fat Diet Regimens: A Systematic Review with GRADE Evaluations
Received: 01-May-2023 / Manuscript No. snt-23-98716 / Editor assigned: 04-May-2023 / PreQC No. snt-23-98716(PQ) / Reviewed: 18-May-2023 / QC No. snt-23-98716 / Revised: 23-May-2023 / Manuscript No. snt-23-98716(R) / Published Date: 30-May-2023 DOI: 10.4172/snt.1000201
Introduction
Type 2 diabetes is a chronic condition that affects millions of people worldwide. It is characterized by high blood sugar levels due to the body’s inability to produce or use insulin effectively. In recent years, low-carbohydrate diets have gained popularity as a potential therapeutic approach for managing type2 diabetes [1]. This article will examine the effects of low-carbohydrate diet therapies on metabolic control in type 2 diabetics. Diet is an essential component of diabetes management, and low-carbohydrate diets have gained popularity as a potential therapeutic approach for managing type2 diabetes [2].
Low-carbohydrate diets, also known as carbohydrate-restricted diets, restrict the intake of carbohydrates while increasing the consumption of protein and fat [3]. The goal of this dietary approach is to decrease insulin requirements and improve blood sugar control. Several studies have investigated the impact of low-carbohydrate diets on metabolic control in type 2 diabetics. One potential mechanism is through the reduction of postprandial glucose excursions.Postprandial glucose excursions are spikes in blood sugar levels that occur after meals. These spikes are associated with an increased risk of cardiovascular disease and other diabetes-related complications [4- 8].Low-carbohydrate diets may reduce postprandial glucose excursions by limiting the amount of glucose entering the bloodstream.
Several studies have investigated the effects of low-carbohydrate diets on metabolic control in type 2 diabetics. A study published in the Annals of Internal Medicine in 2004 compared the effects of a lowcarbohydrate diet to a low-fat diet in type 2 diabetics [9, 10]. The study found that the low-carbohydrate diet resulted in greater weight loss and improved glycaemic control compared to the low-fat diet.
A study published in the Journal of Nutrition in 2005 investigated the effects of a low-carbohydrate, high-protein diet on metabolic control in type 2 diabetics. The study found that participants on the low-carbohydrate diet had significant improvements in glycaemic control, insulin sensitivity, and blood pressure compared to those on a high-carbohydrate diet [11, 12].
Another study published in the Annals of Internal Medicine in 2004 compared the effects of a low-carbohydrate diet to a low-fat diet in type 2 diabetics. The study found that the low-carbohydrate diet resulted in greater weight loss and improved glycaemic control compared to the low-fat diet [13].
A more recent meta-analysis published in the Journal of the Academy of Nutrition and Dietetics in 2019 evaluated the effects of low-carbohydrate diets on glycaemic control and cardiovascular risk factors in type 2 diabetics [14]. The study found that low-carbohydrate diets led to significant improvements in glycaemic control, including reductions in HbA1c and fasting blood glucose levels, as well as improvements in cardiovascular risk factors such as blood pressure and triglyceride levels.
Despite the promising findings, there are some potential concerns with low-carbohydrate diets. One concern is that a diet high in protein and fat may increase the risk of heart disease [15]. However, some studies have found that low-carbohydrate diets may actually improve cardiovascular risk factors. Another concern is that low-carbohydrate diets may be difficult to sustain long-term, leading to weight regain and potential negative impacts on metabolic control [16].
Conclusion
Low-carbohydrate diets appear to be a promising therapeutic approach for managing type 2 diabetes, with several studies demonstrating improvements in glycemic control and other metabolic parameters. However, more research is needed to determine the longterm effects of this dietary approach on overall health and sustainability. As with any dietary change, it’s important to consult with a healthcare professional before starting a low-carbohydrate diet, especially if you have any underlying health conditions.
Acknowledgement
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Conflict of Interest
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References
- Jang W, Kim H, Lee B, Chang N (2018) Maternal fruit and vegetable or vitamin C consumption during pregnancy is associated with fetal growth and infant growth up to 6 months : results from the Korean Mothers and Children ’ s Environmental Health ( MOCEH ) cohort study 1-11.
- Yazew T, Daba A (2020) Advanced Techniques in Biology & Medicine Health Bene ts of Fruit and Vegetables Consumption : Preventive Implications for Non- communicable Diseases in Ethiopia.
- Miller V, Yusuf S, Chow CK, Dehghan M, Corsi DJ, et al. (2016) Availability, affordability, and consumption of fruits and vegetables in 18 countries across income levels: findings from the Prospective Urban Rural Epidemiology (PURE) study. Lancet Glob Heal 4: 695-703.
- Fao J (2004) Fruit and Vegetables. Workshop WHO 1-3.
- McLeroy KR, Bibeau D, Steckler A, Glanz K (1988) An ecological perspective on health promotion programs. Health Educ Q 15: 351-377.
- Green LW, Richard L, Potvin L (1996) Ecological foundations of health promotion. Am J Health Promot 10: 270-281.
- Story M, Kaphingst KM, Robinson-O'Brien R, Glanz K (2008) Creating healthy food and eating environments: policy and environmental approaches. Annu Rev Public Health 29: 253-272.
- Merriam SB, Tisdell EJ (2016) Six common qualitative research designs. Qualitative Research Jossey-Bass 22-42.
- Ahrén B (2011) GLP-1 for type 2 diabetes. Experimental cell research 317: 1239-1245.
- World Obesity. (2015). How is obesity measured.
- Rotter V, Nagaev I, Smith U (2003) Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-α, overexpressed in human fat cells from insulin-resistant subjects. J Biol Chem 278: 45777-45784.
- Herman W, Ye W, Griffin S, Simmons R, Davies M, et al. (2015) Early Detection and Treatment of Type 2 Diabetes Reduce Cardiovascular Morbidity and Mortality: A Simulantion of the Results of the Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in Primary Care (Addition Europe). Diabetes Care 38: 1449-1455.
- Gatta G, Botta L, Sánchez MJ, Anderson LA, Pierannunzio D, et al. (2015) Prognoses and improvement for head and neck cancers diagnosed in Europe in early 2000s: The EUROCARE-5 population-based study. Eur J Cancer 51: 2130-2143.
- Gupta B, Johnson NW, Kumar N (2016) Global epidemiology of head and neck cancers: a continuing challenge. Oncology 91:13-23.
- Ridge JA (2015) Head and Neck Cancer, An Issue of Surgical Oncology Clinics of North America. E-Book. Elsevier Health Sciences 24: 15-16.
- Davies L, Welch HG (2006) Epidemiology of head and neck cancer in the United States. Otolaryngol Head Neck Surg 135:451-457.
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Citation: Ether VZ (2023) Effects of Low-Carbohydrate Diet Therapies onMetabolic Control in Type 2 Diabetics as Compared to Low-Fat Diet Regimens: ASystematic Review with GRADE Evaluations. J Nutr Sci Res 8: 201. DOI: 10.4172/snt.1000201
Copyright: © 2023 Ether VZ. This is an open-access article distributed under theterms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.
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