Journal of Clinical & Experimental Neuroimmunology
Open Access

Adolescent health; Cannabis; Drug abuse; Illicit drugs; Nicotine; Opioids

Introduction

In the general American population, drug use disorders have a lifetime prevalence of roughly 10%, which translates to more than 23 million persons who struggle with problematic drug use. There are significant percentages of other co-occurring substance use disorders, and about one-third of adult Americans will at some point in their lives fit the criteria for an alcohol use problem [1]. Only a small percentage of people with alcohol or drug use disorders obtain any treatment, despite the well-known negative effects of addiction on physical health, psychology, and quality of life.

Following an upsurge in opioid overdoses that resulted in more than 42 000 deaths in 2016-a record high the US Department of Health and Human Services declared the US opioid epidemic a public health emergency in 2017 and unveiled a 5-point approach to address the opioid crisis. As synthetic opioids flooded the black market for drugs, the number of overdose deaths and health effects associated with substance use, especially opioid use, continued to rise sharply [2]. The coronavirus disease 2019 (COVID-19) pandemic, which presented difficulties for the healthcare system and exposed vulnerabilities for those who use these substances, further brought home the stark realities of the risks of untreated substance use.

NIDA works to insure that the followingcross-cutting themes are addressed across institute programs and enterprise

a) Advancing introductory exploration on neuroscience and biology

b) Using technology

c) Driving invention

d) Adding scientific rigor and reproducibility

e) Erecting a strong, different, multidisciplinary scientific pool

f) promoting collaboration

g) encouraging data and resource sharing (data adjustment) supporting health equivalency

h) Adding the real- world applicability of exploration(restatement)

Discussion

The most used substances in America among kids and adults are nicotine, alcohol, and cannabis, and most people there use drugs. 60.1% of Americans aged 12 and older used a drug in the previous month, of which 50.8% drank alcohol, 21.1% used tobacco, and 13% used illicit drugs. Below, we give a quick review of current trends in substance use, talk about how it affects society and the health care system, and look at how the pandemic has affected people's ability to get treatment for substance abuse [3].

The National Survey of Drug Use and Health, the National Epidemiologic Survey on Alcohol and Related Conditions, and the Monitoring the Future Study are the principal data sources for information on alcohol and drug use in the United States. Providing upto- date data on "national indicators of substance use and mental health among the civilian, noninstitutionalized population aged 12 or older in the United States," the Substance Abuse and Mental Health Services Administration has been publishing an annual report that highlights key findings from the National Survey of Drug Use and Health since 1971. Data on cigarettes, alcohol, illegal drugs, prescription drug abuse, and mental health in the United States are available at the national and state levels through the National Survey on Drug Use and Health. To provide accurate data on the longitudinal patterns of substance use, the survey's main goals in 2019 included 70,000 randomly selected Americans. These included tracking use trends, evaluating the effects of substance use and addiction, and identifying the groups most at risk for negative consequences.

To understand the prevalence, risk factors, health disparities, economic costs, and gene-environment interactions related to alcohol use disorders and their associated disabilities, the National Epidemiologic Survey on Alcohol and Related Conditions, a nationally representative survey of 46 500 adult Americans, focuses on data collection regarding alcohol use disorders and their associated disabilities. The Monitoring the Future Study, which is funded by the National Institute on Drug Abuse and involves a nationally representative sample of 40 000 to 50 000 eighth, tenth, and twelve grade in-school students across more than 400 schools nationwide, has been tracking adolescent students' attitudes toward drug and alcohol use since 1975.

Nicotine

After reaching a peak in the middle of the 1990s, teen smoking has been on the decline through 2019. There have been significant decreases in the commencement of cigarette use and increases in the perceived dangers of smoking, and the percentage of students reporting any cigarette smoking in the past 20 days has dropped from 84% to 89%. The sharp rise in teen vaping offset these encouraging trends in nicotine reduction. Between 2015 and 2017, vaping of nicotine doubled, and that of cannabis increased by 2- to 3-fold. In 2019, vaping was among the most prevalent teen drug use behaviours [4].

Alcohol

According to the Monitoring the Future Study poll, teen drinking has significantly decreased over the past 30 years, paralleling declines in adolescent smoking. At its lowest point in 1992, the prevalence of binge drinking decreased by about a third. By the time they were 12 to 17 years old, 9% of kids and 55.1% of young adults had consumed alcohol. Alcohol use disorders were reported to be prevalent in 1.7% of 12- to 17-year-olds, 9.3% of 18- to 25-year-olds, and 8% of adolescents overall, according to the National Survey on Drug Use and Health and the National Epidemiologic Survey on Alcohol and Related Conditions [5]. Large rises in alcohol use disorder rates during the past ten years, with 13.9% of individuals fulfilling the criteria for the past year and 29% receiving a lifetime diagnosis, were indicative of this trend.

Conclusion

While teen drinking and tobacco usage have significantly down, cannabis use overall, and the use of nicotine vape products have both grown. While cannabis use is more common than opiate use, opioid usage is much riskier and is responsible for most drug-related fatalities. Nevertheless, fewer opioid prescriptions are being filled on a regular basis. The effects of abusing substances go beyond the negative effects they have on the users' health. The effects extend to their families and numerous other members of their communities, and these detrimental effects are more prevalent in places with few resources. Although there are therapies for substance use disorders, only a small fraction of people actually receives them since access to care can be difficult in underserved areas. While border barriers and other steps have made some available illicit products more harmful, the COVID-19 pandemic has made it difficult for people to access safer areas to take drugs and to access treatment.

1. Savage CO, Harper L, Cockwell P, Adu D, Howie AJ (2000) ABC of arterial and vascular disease: vasculitis. BMJ 320:1325-8. 

       Indexed at, Google Scholar, Crossref

2.  Salvarani C, Crowson CS, O'Fallon WM, Hunder GG, Gabriel SE (2004) Reappraisal of the epidemiology of giant cell arteritis in Olmsted County, Minnesota, over a fifty-year period. Arthritis Rheum 51:264-8. 

        Indexed at, Google Scholar, Crossref

3. Hunder GG, Arend WP, Bloch DA, Calabrese LH, Fauci AS et al (1990) The American College of Rheumatology criteria for the classification of vasculitis. Introduction. Arthritis Rheum 33:1065-7. 

       Indexed at, Google Schola, Crossref

4. Sakane T, Takeno M, Suzuki N, Inaba G (1999)  Behçet's disease. N Engl J Med 341:1284-91.

        Indexed at, Google Scholar, Crossref

5. Barron KS, Shulman ST, Rowley A, Taubert K, Myones BL et al. (1999) Report of the National Institutes of Health Workshop on Kawasaki Disease. J Rheumatol  26:170-90. 
      

Google Scholar