ISSN: 2572-4118

Breast Cancer: Current Research
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Editorial   
  • Breast Can Curr Res 2023, Vol 8(6): 6

An Unusual Case of Breast Cancer Scalp Metastasis

Shi-lin Lu*
Department of Neurosurgery, Dalian, China
*Corresponding Author: Shi-lin Lu, Department of Neurosurgery, Dalian, China, Email: Shi.ll8090@gmail.com

Received: 01-Dec-2023 / Manuscript No. bccr-23-123515 / Editor assigned: 04-Dec-2023 / PreQC No. bccr-23-123515 / Reviewed: 18-Dec-2023 / QC No. bccr-23-123515 / Revised: 22-Dec-2023 / Manuscript No. bccr-23-123515 / Published Date: 29-Dec-2023 QI No. / bccr-23-123515

Abstract

Breast cancer is a complex and heterogeneous disease that can metastasize to various organs, with scalp involvement being an uncommon manifestation. This case report presents a rare occurrence of breast cancer metastasis to the scalp in a 56-year-old female patient with a history of invasive ductal carcinoma. The patient presented with a rapidly growing scalp nodule, which was initially misdiagnosed as a benign lesion. Subsequent investigations revealed the presence of metastatic breast cancer, highlighting the importance of considering unusual sites of metastasis in breast cancer patients. This case emphasizes the need for vigilant clinical evaluation and appropriate imaging studies to detect rare metastatic lesions, allowing for timely intervention and personalized treatment strategies.

Introduction

Breast cancer remains a leading cause of cancer-related morbidity and mortality worldwide, characterized by its heterogeneity and ability to metastasize to distant sites. While common sites of metastasis include bones, lungs, and liver, unusual presentations continue to challenge clinicians in their diagnostic approach. Scalp metastasis from breast cancer is an infrequent occurrence, comprising a small percentage of metastatic cases. This report describes a unique case of breast cancer metastasis to the scalp in a postmenopausal woman with a history of invasive ductal carcinoma. The rarity of scalp involvement in breast cancer metastasis necessitates a thorough understanding of atypical presentations, as they may elude conventional diagnostic pathways. The aim of this report is to contribute to the growing body of literature on unusual metastatic sites in breast cancer and underscore the significance of comprehensive clinical assessments in detecting and managing such cases. Improved awareness and early recognition of unusual metastatic patterns can guide clinicians in providing more effective and tailored therapeutic interventions for patients with advanced breast cancer [1-3].

Discussion

The occurrence of breast cancer metastasis to the scalp is a rare phenomenon and presents diagnostic and therapeutic challenges for clinicians. In this case, the patient’s initial presentation with a rapidly growing scalp nodule, initially misinterpreted as a benign lesion, underscores the importance of considering uncommon sites of metastasis in breast cancer patients. The delay in accurate diagnosis highlights the need for heightened clinical suspicion and thorough investigations when confronted with unusual clinical presentations.

Several factors contribute to the atypical metastasis of breast cancer, including the tumor’s molecular subtype, the presence of specific biomarkers, and individual variations in the tumor microenvironment. Understanding the underlying mechanisms of metastasis to unconventional sites is crucial for developing targeted therapeutic strategies. Further research into the molecular and genetic profiles of breast cancer cells with a propensity for scalp metastasis may provide insights into the pathophysiology of this uncommon phenomenon.

The management of scalp metastasis involves a multidisciplinary approach, including surgical excision, radiation therapy, and systemic treatments. In this case, a combination of surgery and systemic therapy was employed to address the metastatic lesion. The response to treatment, the patient’s overall prognosis, and potential side effects of therapeutic interventions must be carefully monitored [4-8].

Conclusion

Breast cancer metastasis to the scalp is a rare manifestation that requires heightened clinical awareness and a comprehensive diagnostic approach. This case emphasizes the significance of considering unusual sites of metastasis in breast cancer patients, especially when presented with atypical clinical features. Timely and accurate diagnosis is crucial for implementing appropriate therapeutic interventions and improving patient outcomes. As our understanding of the molecular and genetic factors influencing metastatic patterns grows, clinicians can better tailor treatment strategies for patients with breast cancer. Continued research into the mechanisms underlying rare metastatic events, such as scalp involvement, is essential for advancing our knowledge and improving the management of advanced breast cancer. Ultimately, this case underscores the need for vigilance, ongoing research, and a collaborative, multidisciplinary approach to address the complexities of metastatic breast cancer.

Acknowledgment

None

Conflict of Interest

None

References

  1. Al-Mahmood S, Sapiezynski J, Garbuzenko OB, Minko T (2018) Metastatic and triple-negative breast cancer: challenges and treatment options. Drug Deliv Transl Res 8: 1483-1507.
  2. Indexed at, Google Scholar, Crossref

  3. Chaudhary LN (2020) Early stage triple negative breast cancer: management and future directions. Semin Oncol 47: 201-208.
  4. Indexed at, Google Scholar, Crossref

  5. Bianchini G, Balko JM, Mayer IA, Sanders ME, Gianni L (2016) Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease. Nat Rev Clin Oncol 13: 674-690.
  6. Indexed at, Google Scholar, Crossref

  7. Melero I, Castanon E, Alvarez M, Champiat S, Marabelle A (2021) Intratumoural administration and tumour tissue targeting of cancer immunotherapies. Nat Rev Clin Oncol 18: 558-576.
  8. Indexed at, Google Scholar, Crossref

  9. Cabral H, Kinoh H, Kataoka K (2020) Tumor-targeted nanomedicine for immunotherapy. Acc Chem Res 53: 2765-2776.
  10. Indexed at, Google Scholar, Crossref

  11. Lee H, Kim SW, Kwon DY, Kang HW, Jung MJ, et al. (2021) Near-infrared Transillumination and Photodynamic Therapy Using Hypericin in Animal Laryngeal Tumors. Tissue Eng Regen Med 18: 941-951.
  12. Indexed at, Google Scholar, Crossref

  13. Grassi ES, Ghiandai V, Persani L (2021) Thyroid Cancer Stem-Like Cells: From Microenvironmental Niches to Therapeutic Strategies. J Clin Med 10: 1455.
  14. Indexed at, Google Scholar, Crossref

  15. Choi JS, Heang Oh S, Kim YM, Lim JY (2020) Hyaluronic acid/alginate hydrogel containing hepatocyte growth factor and promotion of vocal fold wound healing. Tissue Eng Regen Med 17: 651-658.
  16. Indexed at, Google Scholar, Crossref

Citation: Lu S (2023) An Unusual Case of Breast Cancer Scalp Metastasis. BreastCan Curr Res 8: 225.

Copyright: © 2023 Lu S. This is an open-access article distributed under theterms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.

Top