A Review on Immunity and Vaccination: Basic Principle
DOI: 10.4172/2471-9846.1000281
Keywords: Vaccine; Antibody; Immunity; Plasma
In our body immune system is an extremely important process and it is act as a defence mechanism about identify the foreign organism and destroy it. The process of Immunisation prevents disease by respond more rapidly to attack on foreign body and increase the immune response against particular organism. The largest one is the skin it act as a strong physical barrier for foreign body do not enter into the skin [1]. But some organisms are able to penetrate and enter into the undamaged skin. Some other physical barriers and a different chemical defences actively involved in this system.
On the basis of the mechanism, the immune system is divided into two main types. These are the innate immune system and it is also knowm as general resistance system. The secon type of immnune system is adaptive immune system. These two innate system and the adaptive system rapidly interact with foreign body to protect our body from infection [2-5]. During the immune response progresses, the active plasma cells will begin producing IgG antibodies to specific to specific antigen. However IgM is the first antibody produced against antigen and it is a much larger antibody than other antibodies. IgG is also called neutralizing antibody. IgG binds more strongly to the antigen.
A passive immunity transfer from mother to newborn baby through the placenta . Adults can also get passive immunity by products such as immune globulin also called antibody-blood products, such type of products can given when need immediate protection from a specific infection is needed. The advantage of passive immunity is it gives immediate protection, but active immunity it will takes time to develop the immunity against the infection. The vaccine can directly increases the activation of innate immunity. The antibody responses are very strong by taking live vaccines that are naturally adjuvanted. After taking vaccine It will take several weeks for a vaccine to help protection your baby against infection.
Some evidence shows that in all types of infections,Vitamin A deficiency is associated, with both the innate and adaptive immune systems. However, it is associated with intake of healthy diet that influences immune responses in child is poorly understood and complex ways. Likewise, the relationship between obesity and immunity system is still poorly understand. The chronic inflammation linked with obesity might affect the vaccine-induced immunity. But practioners should clearly understand the relationship between malnutrition or obesity and immune responses by conducting different experiments using different parameters of innate immune response and adaptive immune responses can be evaluated by new genetic technologies, including the use of advanced molecular biology. Recent studies shows that, develop vaccines against global pandemics infctions for example such as infection with human immunodeficiency virus (HIV) is failed because tehre is no clear understand machanism and immunological process by which type of vaccines can more effective against human immunodeficiency virus.
References
- 1. Almutairi H (2020) Herd Immunity without the FrailSheep.Epidemiol Sci 10: 382.
- 2. Yadav SI (2020) Immunity: Entry of Antigens making the Immune System more D efensive. 4(2): 125.
- 3. Lu ZW, Hua JQ, Han LT, Zhang TT, Wei WJ, et al. (2019) IL-10 Restores MHC Class I Expression and Interferes Tumor Immunity in Papillary Thyroid Cancer with Concomitant Hashimoto’s Thyroiditis. Diagn Pathol Open 4: 152.
- 4. Ahmad M, Dhole T, Kunwar A, Vishwakarma R, Soni GK, et al. (2018) Intestinal Mucosal Immunity against Polioviruses in Adolescent and Adult Populations: A Community Based Cross-sectional Study in India. J Mucosal Immunol Res 2: 111.
- 5. Kim SC (2017) How to Grow Immunity? J Tradit Med Clin Natur 6:e139.
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