A Brief Note on Ischemic Heart Disease
Received: 04-Jan-2023 / Manuscript No. ECR-23-86721 / Editor assigned: 06-Jan-2023 / PreQC No. ECR-23-86721 (PQ) / Reviewed: 20-Jan-2023 / QC No. ECR-23-86721 / Revised: 23-Jan-2023 / Manuscript No. ECR-23-86721 (R) / Published Date: 30-Jan-2023 DOI: 10.4172/2161-1165.1000480
Abstract
The most common cardiovascular disease is coronary artery disease (CAD), which is also known as coronary heart disease (CHD), ischemic heart disease (IHD), myocardial ischemia, or simply heart disease. It is caused by the accumulation of atherosclerotic plaque in the arteries of the heart. Types of CAD include stable angina, unstable angina, myocardial infarction, and sudden cardiac death. Shortness of breath may also occur, and sometimes no symptoms are present. In many cases, the first sign is a heart attack. Other complications include heart failure or an abnormal heartbeat. Risk factors include smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, depression, and excessive alcohol consumption.
Keywords
Cardiovascular disease; Diabetes
Introduction
A number of tests may help with diagnosis, including: There is limited evidence for screening people who are at low risk and do not have symptoms. Treatment involves the same measures as prevention. Additional medications such as antiplatelets (including aspirin), beta blockers, or nitroglycerin may be recommended. Procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) may be used in severe disease. In those with stable CAD, it is unclear Chest pain or discomfort that occurs frequently during activity, after eating, or at other predetermined times is the most common symptom. This condition is known as stable angina and is connected to heart artery narrowing. Angina can also be characterized by chest tightness, heaviness, pressure, numbness, fullness, or squeezing. Unstable angina is one in which the intensity, character, or frequency of the pain fluctuates. Myocardial infarction may be preceded by unstable angina. Angina, shortness of breath, sweating, nausea or vomiting, and light-headedness are signs of a heart attack or myocardial infarction, and immediate emergency medical services are crucial. With advanced disease, the narrowing of coronary arteries reduces the supply of oxygen-rich blood flowing to the heart, which becomes more pronounced during strenuous activities during which the heart beats faster. For some, this reduces the supply of oxygen-rich blood flowing to the heart and causes severe Ischemia or oxygen deprivation-induced cell starvation, occurs when blood flow to the heart is restricted. A myocardial infarction-also known as a heart attack—may result in the death of muscle cells in the heart due to a lack of oxygen. Without the regrowth of heart muscle cells, it results in damage, death, and eventually scarring of the heart muscle. Coronary artery disease typically develops when a portion of the smooth, elastic lining inside a coronary artery-the arteries that supply blood to the heart muscle-develops atherosclerosis. Transient ischemia can result in the induction of a ventricular arrhythmia, which may progress to a potentially fatal heart rhythm known as ventricular fibrillation [1-5].
Discussion
A plaque is formed when the lining of an artery hardens, stiffens, and accumulates calcium, fatty lipids, and abnormal inflammatory cells due to atherosclerosis. Inducing the early stage of coronary arteriosclerosis and stiffening the arteries, calcium phosphate (hydroxyapatite) deposits appear to play a significant role in the muscular layer of the blood vessels. A so-called metastatic mechanism of calciphylaxis that occurs in chronic kidney disease and hemodialysis can demonstrate this. Despite the fact that these individuals have kidney dysfunction, nearly half of them die from coronary artery disease. Plaques can be compared to large "pimples" that protrude into an artery's channel and partially block blood flow. Individuals with coronary artery disease may only have one or two plaques, or they may have dozens of plaques scattered throughout their arteries. Cardiac syndrome X is chest pain (angina pectoris) and discomfort in the chest in people who do not show signs of blockages in the larger coronary arteries of their hearts when an angiogram (coronary angiogram) is performed. The exact cause of cardiac syndrome X is unknown. Chronic total occlusion (CTO) is a more severe form when a coronary artery is completely obstructed for more than three months. Microvascular dysfunction or epicardial atherosclerosis are two possible explanations. For unknown reasons, women are more likely than men to have it; However, hormones and other female-specific risk factors may play a role. There are numerous heart disease risk factors: Age, sex, tobacco use, inactivity, non-alcoholic fatty liver disease, excessive alcohol consumption, an unhealthy diet, obesity, genetic predisposition and family history of cardiovascular disease, elevated blood pressure (hypertension), elevated blood sugar (diabetes mellitus), elevated blood cholesterol (hyperlipidemia), undiagnosed celiac disease, psychosocial factors, poverty and low educational status, air pollution, and poor sleep are all risk factors. However, many important cardiovascular risk factors can be changed by changing one's lifestyle, changing one's social life, or taking drugs to treat conditions like diabetes, hypertension, and hyperlipidemia. Obese people are more likely to develop atherosclerosis in their coronary arteries. Acute coronary syndrome is usually diagnosed in the emergency department, where ECGs can be done sequentially to find "evolving changes" (indicating ongoing damage to the heart muscle). If ECGs show elevation of the "ST segment," which is strongly indicative of an acute myocardial infarction (MI) in the context of severe typical chest pain, the diagnosis is clear [6-10].
Conclusion
This is known as a STEMI (ST-elevation MI) and is treated as an emergency with either thrombolysis ("clot buster" medication) or urgent coronary angiography and percutaneous coronary intervention (angioplasty with or without stent insertion). Cardiac markers (blood tests that identify heart muscle damage) are used to identify heart damage in the absence of ST-segment elevation. Chest pain is considered a "non-ST elevation MI" (NSTEMI) if there is evidence of damage (infarction). The term "unstable angina" is used when there is no evidence of damage. In most cases, this procedure requires admission to the hospital and close monitoring in a coronary care unit for potential complications (such as cardiac arrhythmias, or irregular heartbeats). Stress testing or angiography may be used to diagnose and treat coronary artery disease in patients who have had an NSTEMI or unstable angina, depending on the risk assessment.
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Citation: Giang H (2023) A Brief Note on Ischemic Heart Disease. Epidemiol Sci,13: 480. DOI: 10.4172/2161-1165.1000480
Copyright: © 2023 Giang H. This is an open-access article distributed under theterms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.
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