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PubMed NLM ID: 101713528
Journal of Mucosal Immunology Research is an open access peer reviewed journal that deals with different aspects of mucosal innate immune system. This immunology journal publishes research findings on the mucosal membrane associated microbial flora, elucidation of the mucosal immune response as well as mucosal diseases, vaccines, mucosal immunization, mucosal inflammatory diseases, immune responses at mucosal associated lymphoid tissues, effects of dietary components and probiotics on the function of the mucosal immunity. Manuscripts leading to the development of clinical mucosal immunological drugs are welcome.
Journal of Mucosal Immunology Research uses the Editorial Tracking System for quality in review process. Editorial Tracking is an online manuscript submission, review and tracking systems used by most of the best open access journals. Review processing is performed by the editorial board members of journal or outside experts; at least two independent reviewers approval followed by editor's approval is required for acceptance of any citable manuscript.
submit manuscript online using https://www.scholarscentral.org/submissions/mucosal-immunology-research.html or as an e-mail attachment to manuscripts@omicsonline.com
Mucosal immune cells are pivotal in maintaining homeostasis and responding to pathogens at mucosal surfaces. Key cell types include dendritic cells, which capture and present antigens to T cells, and macrophages, which phagocytize pathogens and secrete inflammatory cytokines. B cells produce antibodies specific to mucosal antigens, while T cells orchestrate immune responses and contribute to tolerance. These cells interact within mucosal-associated lymphoid tissues (MALT) to regulate immune responses and maintain barrier integrity. Research is focusing on their roles in immune regulation, response to infections, and contributions to autoimmune and inflammatory diseases, aiming to develop targeted therapies for mucosal disorders.
Most irresistible operators enter the body at mucosal surfaces and accordingly mucosal safe reactions work as a first line of safeguard. Defensive mucosal resistant reactions are most viably incited by mucosal inoculation through oral, nasal, rectal or vaginal courses, however by far most of antibodies being used today are directed by infusion. Flow examine is giving new bits of knowledge into the capacity of mucosal tissues and the exchange of natural and versatile invulnerable reactions that outcomes in resistant security at mucosal surfaces. These advances guarantee to quicken the improvement and testing of new mucosal antibodies against numerous human maladies including HIV/AIDS.
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Journal of Vaccines & Vaccination, Rheumatology: Current Research, Immunome Research, Journal of Allergy & Therapy, Journal of AIDS & Clinical Research, Allergy: European Journal of Allergy and Clinical Immunology, Autoimmunity Journal, Clinical and Experimental Immunology, Autoimmunity Reviews, Clinical Immunology, Current Opinion in Allergy and Clinical Immunology, Current Opinion in Immunology, Journal of Asthma.
Mucosal Immunology involves the study of immune system response that occurs at the mucosal membrane covering the intestine, urogenital tract and the respiratory system. The mucosal immune system provides primary protection against external pathogens. It is tolerant to the internal non-harmful microbes. Mucosal immunity develops with age with the colonization of intestinal good flora.
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Autoimmune disorders involve the immune system mistakenly attacking the body's own tissues, causing chronic inflammation and damage. Research in autoimmune disorders focuses on understanding the mechanisms of immune dysregulation, identifying genetic and environmental triggers, and developing targeted therapies. Key areas include exploring the role of mucosal immunity in conditions like celiac disease and systemic lupus erythematosus, and investigating biomarkers for early diagnosis and disease monitoring. Advances in immunotherapy, such as biologics and small molecules, are crucial for managing symptoms and improving quality of life. Personalized medicine approaches aim to tailor treatments based on individual genetic and immunological profiles.
It is the science of vaccine development. It also deals with the safety and effectiveness of vaccine. It relates how the immune system responds to vaccines.
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Oral Immunology explores the immune mechanisms within the oral mucosa, focusing on how the immune system protects against infections, manages inflammation, and maintains oral health. Key areas include the role of oral immune cells (e.g., dendritic cells, T cells) in recognizing pathogens, the impact of oral microbiota on immunity, and the pathogenesis of oral diseases such as periodontitis and oral cancers. Research also investigates mucosal barriers, cytokine responses, and potential therapeutic interventions to enhance oral immune defense or address immune-related oral conditions. Advances in this field aim to improve preventive and therapeutic strategies for oral health and disease management.
Mucosal aggravation commonly alludes to swelling or bothering of the bodily fluid layers. These are zones of the body which deliver bodily fluid with an end goal to sift through microscopic organisms, infections, and different intruders. This incorporates the nasal pits, mouth, throat, eyes, vagina, lungs, and digestion tracts. Aggravation may happen if microscopic organisms or infections cause a disease, if the range is disturbed by allergens or other remote bodies, or because of contagious contamination. Different side effects are frequently present alongside mucosal irritation.
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The versatile insusceptible framework, otherwise called the gained resistant framework or, all the more once in a while, as the particular safe framework, is a subsystem of the general invulnerable framework that is made out of very specific, fundamental cells and procedures that wipe out pathogens or keep their development. The versatile safe framework is one of the two principle resistance techniques found in vertebrates (the other being the intrinsic insusceptible framework). Versatile resistance makes immunological memory after an underlying reaction to a particular pathogen, and prompts an upgraded reaction to consequent experiences with that pathogen. This procedure of obtained invulnerability is the premise of inoculation. Like the natural framework, the versatile framework incorporates both humoral invulnerability segments and cell-intervened resistance parts.
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Allergic Reactions are an abnormal sensitivity to a particular substance like pollen, drugs, food or some other environmental factor. It is a local or systemic inflammatory response to an allergen. Allergy and immunology involves the management of disorders related to the immune system.
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Innate immunity is a non-specific defence mechanism that immediately responds to any antigen or harmful foreign cells in the body. It is an inborn immune system. This immune system comprises of physical barriers like skin, some specific chemicals in blood and some immune system cells that attack foreign cells in the body.
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It is the branch of medical science that deals with the health of digestive system or gastrointestinal tract and its related disorders. Diseases like irritable bowel syndrome, hepatitis C falls under this category of medical science.
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It is the branch of science which studies the immune system response at the gut mucosa. Gut mucosa provides plays to important function- firstly in digestion and secondly immune homeostasis. Gut mucosa protects the body from potentially harmful microbes.
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Macrophages play an important role in immunity and immunological responses. They exhibit a defensive role and have the ability to engulf parasites and microbes by the process of phagocytosis. They also regulate lymphocyte activation and proliferation.
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Immuno-deficiency is a state in which one’s immune system ability to fight infectious disease is lost. Immuno-deficiency can be primary or secondary in nature. Primary immuno-deficiency originates in the immune system and is congenital in nature. Most of the primary immuno-deficiency can be inherited. Secondary immuno-deficiency is also known as acquired immunodeficiency and is triggered by external factors like immunosuppressive agents, environmental toxins etc.
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The Immunomodulation is any process which is utilized to alter immune response to a desired level. Immune response is altered with monoclonal antibodies, cytokines, glucocorticoids, immunoglobulin, ultraviolet light, plasmapheresis or other related agents.
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Immuno-epidemiology studies the effect of inter-individual immune response towards micro and macro-pathogens. It combines individual and population based approaches to create new treatment perspectives.
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Infectious diseases research in mucosal immunology focuses on understanding how pathogens like bacteria, viruses, and parasites interact with mucosal surfaces, such as those in the gastrointestinal, respiratory, and urogenital tracts. Key areas of investigation include the mechanisms by which these pathogens evade the mucosal immune system, the role of mucosal immunity in pathogen clearance, and the impact of infections on mucosal barrier function. Research aims to develop targeted vaccines, therapies, and diagnostic tools that enhance mucosal immune responses and improve prevention and treatment strategies for infectious diseases, addressing global health challenges and emerging pathogens.
It is also known as a common cold. This disease is characterized by swelling of the naso-pharyngeal cavity and back of the throat. It usually affects people with weak immune system.
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Infections that affect the sinuses, throat, airway passages or lungs are included under respiratory tract infections. Upper respiratory tract infections include tonsillitis, sinusitis, and laryngitis while lower respiratory tract infections include bronchitis, pneumonia, bronchiolitis, and tuberculosis.
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OCP is viewed as a subtype of Mucous Membrane Pemphigoid (abridged MMP) and these terms are at times utilized reciprocally. OCP is a sort of immune system conjunctivitis that prompts cicatrization (i.e. scarring) of the conjunctiva. If OCP is left untreated, it can prompt visual deficiency.
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The oral mucosa is the mucous film coating within the mouth and comprises of stratified squamous epithelium named oral epithelium and a basic connective tissue named lamina propria. The oral depression has now and again been depicted as a mirror that mirrors the soundness of the person. Changes characteristic of illness are viewed as modifications in the oral mucosa covering the mouth, which can uncover fundamental conditions, for example, diabetes or vitamin insufficiency, or the nearby impacts of constant tobacco or liquor utilize.
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Intraepithelial Lymphocytes are one of the major components of gut-associated lymphoid tissue in gastrointestinal tract. In mammalian mucosal linings, like gastrointestinal (GI) tract and reproductive tract, it is present in the epithelial layer of mammalian mucosal linings. When there is an attack of antigen, it releases cytokines and results in killing target cells.
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Intestinal Mucosa present on the outer surface of the intestine and is the primary site for foreign antigen found in the food, viruses, parasites, intestinal as well as other bacterial pathogens. It has developed acquired and unique innate immunity to fight with these antigens.
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Gastro-Esophageal Reflux (GERD) is the condition when content of stomach returns back to esophagus. In fact, it is a disorder in digestion that affects the lower part of the Esophageal sphincter. According to the studies, it suggests that this condition occurs due to Hiatal Hernia. Hiatal Hernia is the discomfort happens; when stomach pushes the diaphragm muscle upside.
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Dysbiosis is the condition when there is microbial imbalance occurs. This disease can be seen mostly in the gastrointestinal tract, which can be either small intestine’s bacterial or fungal outgrowth (SIBO) & (SIFO). The reason behind bacterial or fungal growth can be due to incompetence normal body flora such as skin, gut or vaginal. According to studies, this disease is sometimes associated with chronic fatigue syndrome, peritoneal disease, colitis or cancer.
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Mucosal Immunotherapy aims to harness and modulate the immune responses at mucosal surfaces, such as the gastrointestinal tract, respiratory tract, and oral cavity. This approach involves administering antigens or immune-modulating agents directly to mucosal sites to induce protective immunity or tolerance. Research focuses on optimizing delivery methods, enhancing efficacy, and minimizing side effects. Key areas include developing mucosal vaccines for infectious diseases and allergies, using biologics to treat chronic inflammatory conditions like inflammatory bowel disease, and exploring novel therapeutic strategies to correct mucosal immune dysfunction. Mucosal immunotherapy holds promise for targeted and effective treatment of a range of mucosal diseases.
Fast Editorial Execution and Review Process (FEE-Review Process):
Journal of Mucosal Immunology Research is participating in the Fast Editorial Execution and Review Process (FEE-Review Process) with an additional prepayment of $99 apart from the regular article processing fee. Fast Editorial Execution and Review Process is a special service for the article that enables it to get a faster response in the pre-review stage from the handling editor as well as a review from the reviewer. An author can get a faster response of pre-review maximum in 3 days since submission, and a review process by the reviewer maximum in 5 days, followed by revision/publication in 2 days. If the article gets notified for revision by the handling editor, then it will take another 5 days for external review by the previous reviewer or alternative reviewer.Acceptance of manuscripts is driven entirely by handling editorial team considerations and independent peer-review, ensuring the highest standards are maintained no matter the route to regular peer-reviewed publication or a fast editorial review process. The handling editor and the article contributor are responsible for adhering to scientific standards. The article FEE-Review process of $99 will not be refunded even if the article is rejected or withdrawn for publication.
The corresponding author or institution/organization is responsible for making the manuscript FEE-Review Process payment. The additional FEE-Review Process payment covers the fast review processing and quick editorial decisions, and regular article publication covers the preparation in various formats for online publication, securing full-text inclusion in a number of permanent archives like HTML, XML, and PDF, and feeding to different indexing agencies.
Articles published in Journal of Mucosal Immunology Research have been cited by esteemed scholars and scientists all around the world. Journal of Mucosal Immunology Research has got h-index 4, which means every article in Journal of Mucosal Immunology Research has got 4 average citations.
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