Journal of Molecular Pharmaceutics & Organic Process Research
Open Access

Molecular Pharmaceutics focuses on molecular mechanistic approaches to the development of bio-available drugs and delivery systems. Molecular Pharmaceutics concentrates on the combination of the chemical and biological sciences to proceed the development of new drugs and delivery systems. Molecular Pharmaceutics promotes high quality research advancing the understanding of pharmaceutics at molecular level.

Molecular Pharmaceutics & Organic Process Research journal is an open access journal that aims to publish most complete and reliable source of information in the mode of original articles, review articles, case reports, short communications, etc. and provide free access through online without any restrictions or any other subscriptions to researchers worldwide.

This journal creates a platform for the authors to make their contribution towards the journal. Journal of Molecular Pharmaceutics & Organic Process Research (JMPOPR) is a peer reviewed journal that includes a wide range of fields but not limited to Biochemistry, Physical and Pharmaceutical chemistry, Materials science, and Molecular and cell biology, Polymer and materials science, Drug carriers, Pharmaceutical-analysis, Molecular pharmaceutics, Molecular-imaging, Drug delivery, Molecular mobility, In silico modeling in drug development, Drug delivery systems and interfaces etc

This scholarly publishing journal is using Editorial Manager System for quality in review process. Editorial Manager is an online manuscript submission, review and tracking systems. Review process is performed by the editorial board members of Journal of Molecular Pharmaceutics & Organic Process Research or outside experts; at least two independent reviewers approval followed by editor approval is required for acceptance of any citable manuscript. Authors may submit manuscripts and track their progress through the system. Reviewers can download manuscripts and submit their opinions to the editor. Editors can manage the whole submission/review/revise/publish process.

 

Biopharmaceuticals

Biopharmaceuticals are a rapidly evolving class of therapeutic agents derived from biological sources, including proteins, nucleic acids, and cells. Unlike traditional pharmaceuticals, which are typically chemically synthesized, biopharmaceuticals are produced using biotechnological methods such as recombinant DNA technology and cell culture. These drugs include monoclonal antibodies, vaccines, therapeutic proteins (like insulin and growth hormones), and gene therapies. Biopharmaceuticals offer targeted treatment options, often with fewer side effects compared to conventional drugs. They play a crucial role in treating complex diseases such as cancer, autoimmune disorders, and rare genetic conditions. The field is continually advancing with innovations in biologics and personalized medicine, promising more effective and individualized treatment strategies.

Nanomedicine and Nanoparticle Drug Delivery

Nanomedicine refers to the application of nanotechnology in the field of medicine. It involves the use of nanoscale materials, such as nanoparticles, to diagnose, treat, and prevent diseases. The key advantage of nanomedicine lies in its ability to interact with biological systems at the molecular level, leading to more precise and effective treatments.

Nanoparticle drug delivery is a specific application within nanomedicine. It involves using nanoparticles-tiny particles typically ranging from 1 to 100 nanometers in size-to deliver drugs directly to targeted cells or tissues. This targeted approach can enhance the efficacy of drugs while minimizing side effects. Nanoparticles can be engineered to control the release of the drug over time, protect the drug from degradation, and improve its solubility and bioavailability. Common types of nanoparticles used include liposomes, polymeric nanoparticles, and dendrimers. Nanoparticle drug delivery is a promising field that holds the potential to revolutionize the way diseases are treated, particularly in areas like cancer therapy, where targeted drug delivery is crucial for success.

Green Chemistry in Process Research

Green Chemistry in Process Research focuses on designing chemical processes that minimize environmental impact and enhance sustainability. It emphasizes the development of safer chemicals and processes that reduce waste, energy consumption, and the use of hazardous substances. Key principles include the use of renewable resources, efficient reaction conditions, and the design of products that degrade safely. By integrating green chemistry principles, researchers aim to improve process efficiency, reduce environmental footprint, and promote the long-term health of ecosystems. This approach not only supports regulatory compliance but also drives innovation in creating more sustainable chemical manufacturing practices.

 

 

 

 

Pharmacokinetics and Pharmacodynamics

Pharmacokinetics (PK) and pharmacodynamics (PD) are fundamental aspects of drug development and clinical application that focus on how drugs interact with the body and their therapeutic effects. Pharmacokinetics examines the absorption, distribution, metabolism, and excretion of drugs, providing insights into how the body processes these substances over time. It addresses key factors such as drug concentration in the bloodstream, the rate at which drugs are eliminated, and how these processes influence dosing regimens. On the other hand, pharmacodynamics explores the biochemical and physiological effects of drugs on the body, including the mechanisms of action, the relationship between drug concentration and effect, and the desired therapeutic outcomes. By understanding both PK and PD, researchers and clinicians can optimize drug therapy, enhance efficacy, and minimize side effects, leading to more effective and personalized treatment strategies. This integration of PK and PD principles is crucial for advancing medical research and improving patient care across various therapeutic areas.

Catalysis in Organic Synthesis

Catalysis in organic synthesis plays a pivotal role in advancing chemical research and manufacturing by accelerating chemical reactions and enhancing reaction selectivity. Catalysts, which are substances that increase the rate of chemical reactions without being consumed, are crucial in developing efficient and sustainable synthetic processes. In organic synthesis, catalysis enables the formation of complex molecules with high precision, improving yields and reducing the need for harsh reaction conditions. Advances in catalytic methods, such as organocatalysis, transition metal catalysis, and enzyme catalysis, have broadened the scope of reactions and applications. These innovations facilitate the synthesis of pharmaceuticals, agrochemicals, and advanced materials, driving progress in various fields. Continued research into new catalysts and reaction conditions is essential for optimizing processes, minimizing environmental impact, and expanding the potential for innovative synthetic strategies.

Molecular and Cellular Biology

Molecular and Cellular Biology is an interdisciplinary field that connects the fields of chemistry, structure and biology as it understands the life and cellular processes at the molecular level. It is rooted in the investigation of biological processes based on the study of molecules and their interactions in the context of cells and tissues, and also understanding the vast information context of the genome orchestrates the behavior of the cell. It is important to discover the basic mechanisms that allow cells to have differentiated properties and coordinate the activities that form the essential systems that define a living cell.

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Biochemistry & Molecular Biology Journal, Cellular and Molecular Biology, Molecular and Cellular Biology, Pathobiology : journal of immunopathology, molecular and cellular biology, Molecular Biology, Molecular Biology and Evolution, Physiology and Molecular Biology of Plants, Physiology and Molecular Biology of Plants.

Drug Discovery Process

The drug discovery process is method of continuous process of the identification, synthesis, characterization, screening, and assays of drugs for therapeutic efficacy. The important steps of this process understand the cause of a certain disease, determine a drug’s ultimate safety profile, and design a quality drug and its manufacturing process to consistently deliver the intended performance, its non-clinical safety, chemical and pharmaceutical production of new drug that has been approved by the regulatory agencies.

Drug discovery can also involve screening small molecules for their ability to modulate a biological pathway in cells or organisms, without regard for any particular protein target. This process is likely to benefit in the future from an evolving forward analysis of synthetic pathways, used in diversity-oriented synthesis, that leads to structurally complex and diverse small molecules.

Related Journals of Drug Discovery Process

Drug Designing, Advances in Pharmacoepidemiology & Drug Safety, International Journal of Drug Development & Research , Current Drug Discovery Technologies, Drug Discovery Today, Drug Discovery Today: Disease Mechanisms, Drug Discovery Today: Disease Models, Drug Discovery Today: Therapeutic Strategies, Drug Discovery World.

Molecular Pharmacy

Molecular Pharmacy is branch of Pharmaceutical Sciences which focuses on study of the molecular mechanistic understanding and developing of bio-available of delivery and delivery systems of drug, including physical and pharmaceutical chemistry, biochemistry and biophysics, molecular and cellular biology, polymer and materials science. The Main aim of Molecular Pharmacy is to understand the pharmaceutics at its molecular level.

Molecular pharmacy also deals with delivering and maintaining the desired amount of a therapeutic agent at the target site for a desired period of time and with cell-based therapies. The development of a drug or vaccine delivery system that accomplishes this is based on an understanding of their transport properties across biological barriers and subsequent biodistribution as well as the mechanism by which they are metabolized and eliminated.

Related Journals of Molecular Pharmacy

Biochemistry & Pharmacology: Open Access Journal, International Journal of Applied Biology and Pharmaceutical Technology, International Journal of Research and Development in Pharmacy & Life Sciences, Advances in Molecular Toxicology, Algorithms for Molecular Biology, American Journal of Biochemistry and Molecular Biology, American Journal of Physiology - Lung Cellular and Molecular Physiology, American Journal of Respiratory Cell and Molecular Biology, Biochemistry and Molecular Biology Education.

Pharmaceutical Nanotechnology

Pharmaceutical Nanotechnology deals with emerging new technologies for developing customized solutions for drug delivery systems. The drug delivery system positively impacts the rate of absorption, distribution, metabolism, and excretion of the drug or other related chemical substances in the body. In addition to this the drug delivery system also allows the drug to bind to its target receptor and influence that receptor’s signaling and activity.

‘Pharmaceutical nanotechnology’ embraces applications of nanoscience to pharmacy as nanomaterials, and as devices like drug delivery, diagnostic, imaging and biosensor.

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Research & Reviews: Journal of Pharmaceutics and Nanotechnology,  Azerbaijan Pharmaceutical and Pharmacotherapy Journal, Brazilian Journal of Pharmaceutical Sciences, Chinese Pharmaceutical Journal, Pharmacy Journal, Journal of Pharmaceutical Technology, Elsevier Pharmaceutical Journals, Journal Pharmaceutical Science, Pharmacy Journals.

Protein Protein interactions

Pharmacogenomics & Pharmacoproteomics , Proteomics & Bioinformatics, Protein and Peptide Letters, Protein Engineering, Design and Selection, Protein Journal, Advances in Protein Chemistry and Structural Biology, Amino Acids, Peptides and Proteins, Current Protein and Peptide Science. 

Digestion

Digestion is a process of breaking down of large insoluble food molecules into small water-soluble food molecules so that they can be absorbed into the watery blood plasma. Digestion is a form of catabolism process in which enzymes break down food into the small molecules that body can use. These smaller substances are absorbed through the small intestine into the blood stream.

Digestion is important for breaking down food into nutrients, which the body uses for energy, growth, and cell repair. Food and drink must be changed into smaller molecules of nutrients before the blood absorbs them and carries them to cells throughout the body. The body breaks down nutrients from food and drink into carbohydrates, protein, fats, and vitamins.

Related Journals of Digestion

Journal of Gastrointestinal & Digestive System, Journal of Hepatology and Gastrointestinal disorders, American Journal of Physiology - Gastrointestinal and Liver Physiology, Journal of Clinical Gastroenterology, Journal of Gastroenterology, Elsevier Pharmaceutical Journals, Journal Pharmaceutical Science, Journal of Gastroenterology and Hepatology, Journal of Gastrointestinal and Liver Diseases, Journal of Pediatric Gastroenterology and Nutrition.

Catabolism

Catabolism is a process of metabolism in which complex molecules are broken down into simpler one with the release of energy. It is a destructive metabolism usually releases energy that is used to drive chemical reactions.

Catabolism involves all of the metabolic processes that tear down biomolecules, e.g. digestion, cellular respiration, etc.The catabolic process releases energy that works to help maintain proper muscle activity. The oxidation process that occurs during catabolism helps synthesize the necessary chemical building blocks like adenosine triphosphate (ATP).

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Journal of Gastrointestinal & Digestive System, Revista Argentina de Endocrinologia y Metabolismo, Applied Physiology, Nutrition and Metabolism, Diabetes and Metabolism, Expert Opinion on Emerging Drugs, Metabolism: Clinical and Experimental.

Biological Processes

Biological processes are the vital processes occurring in living organisms to live. The biological processes contain any number of chemical reactions or other events those results in a transformation. Regulation of biological processes occurs where any process is modulated in its frequency, extent or rate. Biological processes are regulated by many means for examples, the control of gene expression, protein modification or interaction with a substrate or protein molecule.

A biological process is a recognized series of events or molecular functions. A process is a collection of molecular events with a defined beginning and end.

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Biological Systems: Open Access, Journal of Microbiological Methods, Journal of the Korean Society for Applied Biological Chemistry, Microbiological Research, OnLine Journal of Biological Sciences, Pakistan Journal of Biological Sciences, Russian Journal of Biological Invasions.

Anovulation

Anovulation is a condition where ovary fails to release ova over a period of time generally exceeding 3 months. Therefore, ovulation does not take place. The normal functioning ovary releases one ovum every 25–28 days. This average time between ovulation events is variable, especially during puberty and the peri-menopause period. A woman who does not ovulate at each menstrual cycle is not necessarily going through menopause. Chronic anovulation is a common cause of infertility.

Anovulation can arise from a number of causes, ranging from diet and exercise to complex disruptions in the relationships between tiny glands in the brain that control our most basic functions.One of the cardinal signs of anovulation is irregular or absent menstrual periods.

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Journal of Pharmaceutical Technology, Journal of Womens Health, Scandinavian Journal of Infectious Diseases, Iranian Journal of Clinical Infectious Diseases, Open Infectious Diseases Journal, Problems of Infectious and Parasitic Diseases.

Agglutination

Agglutination is a process of visible expression of the aggregation of antigens and antibodies. These reactions apply to particular test antigens that have been conjugated to a carrier. The carrier could be artificial (example latex or charcoal particles) or biological (example red blood cells). These conjugated particles are reacted with patient serum presumably containing antibodies. The end point of the test is the observation of clumps resulting from that antigen-antibody complex formation.

Agglutination reactions have many applications in clinical medicine. Agglutination reactions can be used to type blood cells for transfusion, to identify bacterial cultures, and to detect the presence and relative amount of specific antibody in a patient’s serum. Agglutination has been commonly used to determine whether a patient had or has a bacterial infection.

Related Journals of Agglutination

Journal Pharmaceutical Science, Pharmacy Journals, Pharmacy Journal, Journal of Innate Immunity.

Erythropoiesis

Erythropoiesis the process which produces red blood cells (new erythrocytes). It is stimulated by decreased O2 in circulation, which is detected by the kidneys, which then secrete the hormone erythropoietin. This hormone stimulates proliferation and differentiation of red cell precursors, which activates increased erythropoiesis in the hemopoietic tissues, ultimately producing red blood cells.

Because of the inability of erythrocytes (red blood cells) to divide to replenish their own numbers, the old ruptured cells must be replaced by totally new cells. They meet their demise because they don’t have the usual specialized intracellular machinery, which controls cell growth and repair, leading to a short life span of 120 days. This short life span necessitates the process erythropoiesis, which is the formation of red blood cells. All blood cells are formed in the bone marrow. This is the erythrocyte factory, which is soft, highly cellar tissue that fills the internal cavities of bones.

Related Journals of Erythropoiesis

Journal of Blood & Lymph, Journal of Blood,Journal of Pharmaceutical Technology, Elsevier Pharmaceutical Journals

Intussusception

Intussusception is a condition where the invagination of a proximal segment of bowel into the distal bowel lumen. This causes the bowel walls to press on one another, blocking the bowel. The commonest occurrence is a segment of ileum moving into the colon through the ileo-caecal valve. It can block the passage of food through the intestine. If the blood supply is cut off, the segment of intestine pulled inside can die. Heavy bleeding may also occur, if a hole develops, infection, shock, and dehydration can take place very rapidly.

Intussusception is the most common abdominal emergency affecting children under 2 years old. Babies and children with intussusception have intense abdominal pain, which often begins suddenly and causes the child to draw the knees up toward the chest. The pain often makes the child cry very loudly. As it eases, the child may stop crying for a while and may seem to feel better. The pain usually comes and goes like this, but can become very strong when it returns.

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Journal of Hepatology and Gastrointestinal disorders, Journal of Gastrointestinal & Digestive System, Journal of Gastrointestinal and Liver Diseases,Elsevier Pharmaceutical Journals, Journal Pharmaceutical Science, Pharmacy Journals. 

Eutrophication

Eutrophication is a state when the environment becomes enriched with nutrients. This can be a problem in marine habitats such as lakes as it can cause algal blooms due to the increased availability of one or more limiting growth factors needed for photosynthesis such as sunlight, carbon dioxide, and nutrient fertilizers. Fertilizers used in farming run-off into nearby water causing an increase in nutrient levels.

Eutrophication may occur naturally but can also be the result of human activity (cultural eutrophication from fertilizer runoff and sewage discharge) and is particularly evident in slow-moving rivers and shallow lakes. Increased sediment deposition can eventually raise the level of the lake or river bed, allowing land plants to colonize the edges, and eventually converting the area to dry land.

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Journal of Ecosystem & Ecography, International Journal of Plant, Animal and Environmental Sciences, Environmental and Experimental Botany, Environmental Earth Sciences, Environmental Pollution, Environmental Research, Environment Asia, Frontiers in Ecology and the Environment, International Journal of Environmental Science and Technology.

Ecchymosis

Ecchymosis is the process of Nonraised skin discoloration caused by escape of blood into the tissues from ruptured blood vessels. The term also applies to the subcutaneous discoloration resulting from seepage of blood within the contused tissue. Ecchymoses can occur in mucous membranes (for example, in the mouth), a small hemorrhagic spot in the skin or a mucous membrane, larger than a petechia, forming a non-elevated, rounded, or irregular blue or purplish patch.

Ecchymosis is not a condition or a disorder and is generally harmless. It is however, a symptom of one or more serious underlying medical condition that needs medical attention and intervention. The onset of ecchymosis can be a mild inflammatory response of the body or can be a more complex medical condition. Ecchymosis is generally the result of blunt trauma that caused the blood vessels to rupture and seep into the thin layer of the skin or in the mucus membrane in the absence of an incision or any break in the skin to allow the blood to go out of the skin surface. The accumulation of blood within the skin layers causes the reddish or purplish discoloration of the skin.

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Bacteriostasis

Bacteriostasis is a process or method of preventing of the growth, reproduction and spread of bacteria, without the bacteria being killed. Bacteriostasis state can be attained by the action of a chemical agent which prevents the growth of bacteria (it keeps them in the stationary phase of growth).

Clindamicin and Chloramphenicol are examples of bacteriostatic antibiotics that slow or stop the bacterial growth, usually by the inhibition of protein synthesis.

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Defoliation

Defoliation: The process of separation of ripened leaves from a branch or stem, this type of falling or shedding of the leaves is commonly known as defoliation. There are many reasons why leaves may be lost, the possible causes include chemicals, pests, diseases, environment and (for deciduous trees and shrubs) autumn and also, to destroy narcotic-producing plants as a tactic against illegal drug production. The chemical defoliating agents are often sprayed over large areas from airplanes.

Defoliation can be productive or destructive. There are several areas where plants grow (roots, leaves, culm, rhizomes, stolons, and crown). But regrowth from the leaves is most important for efficient regrowth after defoliation. For optimal regrowth following defoliation there must be cell division and expansion in certain meristem systems.

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Journal of Plant Pathology & Microbiology, Journal of Plant Biochemistry & Physiology, Plant Physiology & Pathology, Russian Journal of Plant Physiology, Soil Science and Plant Nutrition, Tropical Plant Biology, Tropical Plant Pathology, Zhiwu Shengli Xuebao/Plant Physiology Journal, American Journal of Plant Physiology.

Deossification

Deossification is a process occurring in living organisms which refers to the loss or removal of mineral constituents from bone or osseous tissue. The pattern of deossification is common to many diseases is best explained by topographic and anatomic relationships of circulatory system of bone.

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Journal of Bone Marrow Research, Journal of Bone Reports & Recommendations, Clinical Reviews in Bone and Mineral Metabolism, Journal of Bone and Mineral Metabolism, Journal of Bone and Mineral Research, Open Bone Journal, Bone and Joint Journal, Clinical Cases in Mineral and Bone Metabolism.

Eburnation

Eburnation is described as a specific type of bone sclerosis consisting of a marbled appearance of weight-bearing joints with complete cartilaginous erosion, leaving polished, sclerotic bone as the new articular surface bone, it is commonly seen in patients with osteoarthritis or non-union of fractures.Cross-section of the articulation reveals a narrowed joint space, osteosclerosis and cystic changes overlying the affected bone, which is surrounded by bony and cartilaginous overgrowths (osteophytes/exostoses).

Eburnation describes a degenerative process of bone commonly found in patients with osteoarthritis or non-union of fractures. It is an ivory-like reaction of bone occurring at the site of cartilage erosion. Osteoarthritis is a degenerative disease of the joints characterized largely by central loss of cartilage and compensatory peripheral bone formation (osteophytes). Over time, as the cartilage wears away, bare, subchondral bone is revealed. Eburnation describes the bony sclerosis which occurs at the areas of cartilage loss.

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Introversion

Introversion is one of the major personality traits identified in many theories of personality. introverted tend to be inward turning, or focused more on internal thoughts, feelings and moods rather than seeking out external stimulation. Introversion is generally viewed as existing as part of a continuum along with extraversion.

Related Journals of Introversion

European Journal of Personality, Journal of Personality, Journal of Personality and Social Psychology, Journal of Personality Assessment, Journal of Research in Personality, Personality and Individual Differences, Personnel Psychology, Personality and Social Psychology Review, Personality and Social Psychology Bulletin.