Journal of Molecular Immunology
Open Access

Molecular immunology deals with immune responses at cellular and molecular level. Molecular immunology has been evolved for better understanding of the sub-cellular immune responses for prevention and treatment of immune related disorders and immune deficient diseases. Journal of molecular immunology focuses on the invitro and invivo immunological responses of the host.

Journal of Molecular Immunology focuses on the areas such as immunological disorders, invitro and invivo immunological host responses, humoral responses, immunotherapies for treatment of cancer, treatment of autoimmune diseases such as Hashimoto’s disease, myasthenia gravis, rheumatoid arthritis and systemic lupus erythematosus. Treatment of Immune deficiencies such as hypersensitivities, chronic granulomatous disease, diagnostic immunology research aspects, allografts, etc.. Quality articles are welcome for submission which will aid in attaining high impact factor.

Emerging practices and the experiences in this field needs a critical and thorough discussion to spread the knowledge so that the researchers, immunologists and pharmacist adopt them to pass on the benefits to the needy. The Journal of Molecular Immunology accepts articles in the form of research articles, review articles, short communications, letter to editors, commentaries, case reports, etc. This Immunology journal is a peer reviewed open access scholarly journal dedicated towards distribution of valuable information for the societal benefit.

Journal of Molecular Immunology follows Editorial Manager System for quality in peer review process. Editorial Manager is an online manuscript submission, review and tracking systems used by most of the best open access journals.

OMICS International organizes 1000+ conferences every year across USA, Europe & Asia with support from more than 1000 scientific societies and publishes 700+ open access journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Class II MHC molecule

MHC class II molecules are proteins that are restricted to cells of the immune system called macrophages and lymphocytes.

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Immune response

The reaction of the cells and fluids of the body to the presence of a substance which is not recognized as a constituent of the body itself or as foreign object.

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Immunoproteomics

Immunoproteomics identifies and measures the antigenic peptides or proteins. This techniques used are gel based, array based, mass spectrometry, DNA based, or in silico approaches. Immunoproteomics helps in understanding disease and disease progression, vaccine, and biomarkers.
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Immunoglycomics

Immunoglycomics focuses specifically on understanding how specific types of sugars can influence the immune response and how this knowledge can be applied to improve treatments of disease.

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Immunogenomics

Immunogenomics is analysis based on the genetic basis of susceptibility to complex or polygenic diseases (autoimmune or infectious diseases) and identification of the genetic factor responsible for variable immune response. E.g. Estimated effect of MHC, non-MHC and chemokines.

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Cell signaling and activation

Cell signaling is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. Cell activation is the response towards the incoming cell signal by bringing change in biochemical reactions.

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Immunomodulatory xenobiotics

This are immune modifiers, which modifies the functioning of immune response . examples include calcineurin inhibitors, IMPDH2 inhibitors, mTOR inhibitors, Syk inhibitors, mast cell stabilizers , and aspecific antiproliferative or cytotoxic agents.

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Immunopharmacology

Immunopharmacology is defined as a branch of pharmacology concerned with the application of immunological techniques and theory to the study of the effects of drugs especially on the immune system.

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Chemokines

Chemokines are a family of small cytokines, or signaling proteins secreted by cells. Their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. Examples include Neutrophils are regulated primarily by CXC chemokines.

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Immunogenicity of biopharmaceuticals

Immune response by biopharmaceuticals agents are increasing greatly. The first generation of such products were of non-human origin, such as bovine-insulin, streptokinase or staphylokinase. The more recent preparations include human recombinant DNA products, such as interferon (IFN)α 2a, IFNβ, erythropoietin, insulin and growth hormone.

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Immunotolerance

Immunological tolerance is the failure to react with an immune response to an antigen. It can be Natural or self-tolerance. This is the failure to attack the body's own proteins and other antigens.

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Immunosenescence

Immunosenescence refers to the gradual deterioration of the immune system brought on by natural age advancement. Immune senescence, or the aging of the immune system, particularly its effect on changes in lymphocyte development and function, predisposes older adults to a higher risk of latent virus reactivation. The varicella-zoster virus, for example, the agent responsible for chickenpox in children, remains dormant in nerve cells in the trigeminal and dorsal root ganglia and reactivates in later life to cause shingles and post-herpetic neuralgia.

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Immunoglobulins

Any of a class of proteins produced by plasma cells and lymphocytes present in the serum and cells of the immune system, which function as antibodies by attaching to antigens. Examples include immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM), immunoglobulin D (IgD) and immunoglobulin E (IgE).

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Immunochemistry

Immunochemistry is a branch of chemistry that involves the study of the molecular mechanisms underlying the function of the immune system, especially the nature of antibodies, antigens and their interactions.

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Class I MHC molecules

Major histocompatibility complex (MHC) (IA), group of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances. Class I MHC molecules span the membrane of almost every cell in an organism.

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Clinical & Cellular Immunology Open Access, Immunobiology Open Access, Advances in Antibiotics & Antibodies Open Access, Cell Signaling Open Access, The Journal of Immunology, Brazilian Journal of Medical and Biological Research, Journal of General Virology, Immunopharmacology and Immunotoxicology, Innate Immunity & Immunological Disorders Open Access

Non classical MHC class I molecules

Nonclassical molecules (MHC class IB) exhibit limited polymorphism and expression than MHC Ia. It may be recognised by specific subsets of T-cell receptors or by innate immune receptors. Owing to their recognition by a more restricted set of receptors, MHC‐Ib are able to elicit a rapid response from immune cells and are, therefore, regarded as part of the innate immune system. Some MHC‐Ib act as antigen presenting structures, whereas others are recognised as direct ligands for immune receptors.

Journals Related to Non classical MHC class I molecules
Journal of Transplantation Technologies & Research, Brazilian Journal of Medical and Biological Research, Journal of Oncoimmunology, Journal of Immune Research, Immunochemistry & Immunopathology: Open Access

Molecular Immunology

Molecular Immunology deals with immunological response at the molecular, cellular and functional levels of innate and acquired immunity. It includes immune regulation, cell signaling and Immunochemistry.

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Clinical & Cellular Immunology Open Access, Cellular & Molecular Immunology, Immunobiology Open Access, Immunogenetics: Open Access, Immunotherapy: Open Access, New England Journal of Medicine, Brazilian Journal of Medical and Biological Research, The Journal of Allergy and Clinical Immunology, Journal of Immune Research

Journal of Molecular Immunology is supporting 4th International Conference and Exhibition on Immunology which is going to be held September 28-30, 2015 Houston, USA. The theme of the conference is From Basic Immune Understanding to latest Immunology Breakthroughs.