Miller Fisher Syndrome

Miller-Fisher syndrome (MFS), a rare variant of Guillain-Barré syndrome (GBS), typically presents as the triad of areflexia, ophthalmoplegia, and ataxia. Miller-Fisher syndrome (MFS), a variant of Guillain-Barré syndrome (GBS), first described by Dr. Miller Fisher consists of the triad of ophthalmoplegia, ataxia, and areflexia. In its classical form, the condition is easily diagnosed. The natural course of untreated Guillain-Barré syndrome is progressive in the first two weeks, followed by a plateau of 2-4 weeks. In most cases the recovery is underway after 3-4 weeks of onset. The time for full recovery varies significantly from a few weeks to a few years. The median range of MFS recovery without immunotherapy is 4 (range 1 to 185) months. The usual order of recovery of findings is ataxia gait, followed by ophthalmoplegia, and areflexia. The gait was minimally broad based without any ataxia. At the three-month follow-up by his neurologist, the patient had no gait impairment, and eye movement improved except for left lateral rectus weakness and the patient experienced double vision on left lateral gaze. The rest of neurological examination was normal.

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Last date updated on January, 2025