neurology-2017-scientifictracks-abstracts

12 / 34

Volume 8, Issue 2 (Suppl) J Neurol Neurophysiol
ISSN: 2155-9562 JNN, an open access journal Neurology 2017
March 27-29, 2017
Page 45
Notes:
conferenceseries.com
March 27-29, 2017 Madrid, Spain
11th World Congress on
Neurology and Therapeutics
Electrodiagnosis of the peripheral nerve
In the quest of “Chasing the Neuron”, localization of the peripheral nerve lesion is the primary goal of any neurophysiological
study. Electrodiagnosis is an extension of the clinical neurological examination, without which one may find oneself lost in
maze of peripheral neural axis. An array of different electrodiagnostic modalities are used to trace the neuron from the level of
anterior horn cell in the spinal cord, to its end target organ, the post synaptic muscle. Nerve conduction studies are simple tests
used to assess and localize the sensory and the motor nerves, with sparing of the sensory fibers in lesions that are pre-ganglionic,
due to the residing of the posterior root ganglion away from the spinal foramina. However, in post-ganglionic lesions, both
sensory and motor function is impaired, enabling to localize the lesion all along the plexus or the relevant peripheral nerve.
Electromyography or needle EMG further helps in pinpointing the lesion, by mapping the presence of active denervating
potentials in the muscles supplied by the affected nerve, assess for re-innervation as well as prognosticate recovery. By fatiguing
the neuromuscular junction, in repetitive nerve stimulation, one can assess abnormalities of neuromuscular transmission
and acquire information regarding a pre-synaptic or post-synaptic defect. Further specialized single-fiber electromyography
studies enable to perform meticulous assessment of the jitter from single muscle fiber action potentials. Needle EMG is also
the essence of differentiating a primary muscle origin disorder from an underlying neurogenic process. We summarize the use
of electrodiagnostic modalities in the assessment of peripheral nerve disorders.
Biography
Sajjad Ali completed his training in Clinical Neurophysiology from the West Midlands Denary, UK and then worked as a Physician Consultant at the Queen Elizabeth
Hospital Birmingham (QEHB), where he gained experience in the clinical and electrodiagnostic evaluation of peripheral nerve disorders and developed his special interest
in single-fiber electromyography, under the mentorship of Professor Erik Stalberg (Uppsala, Sweden). Currently, he works in one of the largest healthcare organizations in
KSA, the National Neurosciences Institute, King Fahad Medical City, Riyadh. Other research and special interests of his include EMG-guided Botox injections for spasticity,
neuro-intraoperative monitoring and sleep studies.
Sajjad Ali
King Fahad Medical City, Saudi Arabia
Sajjad Ali, J Neurol Neurophysiol 2017, 8:2 (Suppl)