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Journal of Alzheimers Disease & Parkinsonism received 4334 citations as per Google Scholar report
The changes of insulin signaling, calcium signaling, mitochondrial decline and oxidative stress have been implicated in the hyperphosphorylation of tau protein found in Downs syndrome dementia. Such pathogenic etiologies have clear implications in the prevention and therapy of Down’s syndrome (DS) dementia. The occurrence of methylation defec... Read More»
Review Article: J Alzheimers Dis Parkinsonism 2014, 4:159
DOI: 10.4172/2161-0460.1000159
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