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PrPSc is thought to be the infective agent of TSE, and inactivating the infectivity of PrPSc without using strong reagents is difficult. Although PrPSc is a protease resistant protein, it can be degraded in vitro by the hyperthermophilic protease (Tk-subtilisin) at temperatures above 65ºC through the synergistic effect of heat destabilization ... Read More»
Azumi Hirata, Akikazu Sakudo, Kazufumi Takano, Shigenori Kanaya and Yuichi Koga
Research Article: J Biotechnol Biomater 2015, 5:194
DOI: 10.4172/2155-952X.1000194
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