Journal of Infectious Diseases & Therapy
Open Access

Satoko Nakagomi

School of Health Sciences, Shinshu University, 3-1-1, Asahi, Matsumoto-City, Nagano 390-8621, Japan

Publications

Application of a Protease Inhibitor for the Treatment of Viral Respiratory Infections: Acceptable Concentrations of the Protease Inhibitor Nafamostat and Ammonium Chloride for Direct Administration to the Respiratory Epithelium of Mice

Back ground: Enveloped viruses invade cells by fusing the viral envelope with the cell membrane. Most viral fusion proteins require specific host protease(s) to activate their fusion activity. Many influenza viruses and severe acute respiratory syndrome associated coronaviruses use transmembrane serine protease TMPRSS2 for activation. Protease inhi... Read More»

Satoko Nakagomi

: J Infect Dis Ther

10.4172/2332-0877.1000487

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article