ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
Open Access

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Pragya Sahu

India
Publications

Nilotinib Single-Dose Pharmacokinetics and Pharmacodynamics in Parkinson's Disease Patients

With the strongest affinity for inhibiting Abelson (c-Abl) and Discoidal Domain Receptors (DDR1/2), nilotinib is a broad-based tyrosine kinase inhibitor. According to preclinical data, nilotinib lowers brain alpha-synuclein levels and lessens inflammation in Parkinson's Disease (PD) animals. As we previously demonstrated, nilotinib crosses the Bloo... Read More»

Hari Prasad Sonwani, Pragya Sahu and Rashi Bandey

: J Alzheimers Dis Parkinsonism

10.4172/2161-0460.1000586

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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