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Although acetone, in DESI ionisation generally leads to protein aggregation, in this study we report unexpected multi-proton transfers to lysozyme using this aprotic solvent as a charged spray. The DESI/acetone mass spectrum of lysozyme displays (i) a significant increase in the average charge state (Zav) and (ii) an incomplete H+/Ca2+ exchange, ev... Read More»
Anna Warnet, Nicolas Auzeil and Jean-Claude Tabet
Research Article: J Anal Bioanal Tech 2015, 6:283
DOI: 10.4172/2155-9872.1000283
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