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Macromolecular Design of Platinum Drug Conjugates
Cisplatin and its analogues display common drawbacks such as unfavorable toxicological profile, short blood circulation time and non-specific bio-distribution. Besides that, in biological fluids cisplatin is inactivated by nitrogenand sulphur-containing biomolecules. Drug conjugation to a water soluble polymer is a feasible approach to enhance ther... Read More»
Short Communication: Clinic Pharmacol Biopharmaceut 2014, S2
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