ISSN: 2476-2024

Diagnostic Pathology: Open Access
Open Access

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Citations : 110

Diagnostic Pathology: Open Access received 110 citations as per Google Scholar report

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Lukas Werner

Laboratory of Clinical Pathophysiology, Diabetes Centre, Prague
Czech Republic
Publications

Comprehensive Statistical Analysis of the Pharmacokinetics, Safety and Clinical Benefit Rate of Mitotam in a Single-Center Phase I/Ib Trial in Patients with Metastatic Solid Tumors

Background: Mitochondrially Targeted Tamoxifen (MitoTam), the first mitochondrial inhibitor to disrupt Complex I (CI)-dependent respiration, previously showed antitumor activity against Renal Cell Carcinoma (RCC) with a good safety profile. We investigated the relationships of Pharmacokinetic (PK) parameters, biodistribution and patient baseline di... Read More»

Olga Bartosova, Zuzana Bielcikova, Jan Stursa, Michal Pesta, Jiri Neuzil, Miroslava Bursova, Ondrej Slanar, Irena Stenglova Netikova and Lukas Werner

: Diagnos Pathol Open

10.4172/2476-2024.1000237

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