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Microsatellite Instability (MSI) Testing in Extra-colonic Tumors
Faulty DNA repair due to defects in the mismatch repair genes results in microsatellite instability (MSI). Microsatellites are short tandem repeats that are present throughout the genome and are sensitive to errors during the cell cycle. Malfunctioning of the DNA repair mechanisms many occur as a result of germ line mutations in the MMR genes (MLH1... Read More»
Sanam Husain and Lewis Allen Hassell
Short Communication: J Clin Exp Pathol 2015, 5: 221
DOI: 10.4172/2161-0681.1000221
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