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Keheng Wu
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Aim: Physiologically Based Pharmacokinetic (PBPK) model is developed to (1) simulate clinical trials involving the Drug-Drug Interactions (DDI) between fluconazole and drugs (substrates) metabolized primarily by CYP2C9 and CYP3A, and to (2) support dosing recommendations. Methods: The plasma-concentration profiles were simulated in virtual individ... Read More»
Xue Li, Keheng Wu, Zhou Zhou, Ranran Jia, Youni Zhao, Jingxi Li and Bo Liu
: J Infect Dis Ther
10.4172/2332-0877.1000504Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article
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