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Identification and Treatment of Juvenile Acute Myeloid Leukaemia Stem Cell Splicing Dysregulation
Acute myeloid leukaemia in children (pAML) is characterised by frequent relapses and a dearth of somatic DNA alterations. Splicing dysregulation has not been thoroughly researched in pAML, despite seminal findings showing that splicing factor mutations and mis-splicing fuel therapy-resistant leukaemia stem cell (LSC) production in adults. Here, we ... Read More»
: Arch Sci 2023, 7: 153
10.4172/science.1000153Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article
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