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Ellen M. Welch

U.S.A
Publications

Dual mechanism of action of PTC299 and other DHODH inhibitors in suppressing SARS-CoV-2 replication and cellular cytokine storms

COVID-19, the pandemic arising from the third coronavirus outbreak in the past 20 years, will not be the last. Identifying therapies for COVID-19, and possibly future outbreaks, is of great importance. COVID-19 is characterized by an initial phase of viral replication followed by an excessive pro-inflammatory response (cytokine storm). PTC299 is an... Read More»

Stuart W. Peltz, Elizabeth Goodwin, Marla Weetall, Jason D. Graci, Ellen M. Welch, Kylie O\'Keefe and Allan Jacobson

: J Cytokine Biol

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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