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David Stern

U.S.A
Publications

Induced Activation of the Procoagulant Pathways and the Pathogenesis of Ischemia, Venous Thrombosis

A pathway is outlined through which diminished levels of oxygen activate the transcription factor early growth response-1 (Egr-1) leading to de novo transcription/translation of tissue factor in mononuclear phagocytes and smooth muscle cells, which eventuates in vascular fibrin deposition. The procoagulant response is magnified by concomitant suppr... Read More»

Shi-Fang Yan, Nigel Mackman, Walter Kisiel, David Stern and David Pinsky

: Atheroscler Open Access 2022, 7:5, 182

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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