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Skin Reactions Associated to Phenytoin Administration: Multifactorial Cause
Purpose: Cutaneous reactions can be associated with phenytoin administration. Such reactions can be explained by the formation of reactive species (arene oxide and quinones) capable of interacting covalently with cell macromolecules during phenytoin metabolism. Enzymes involved in reactive species detoxification are polimorphically expressed in hum... Read More»
Marta Vázquez, Pietro Fagiolino, Silvana Alvariza, Manuel Ibarra, Cecilia Maldonado, Raquel González, Amalia Laborde, Manuel Uria, Antonella Carozzi and Carlos Azambuja
Research Article: Clin Pharmacol Biopharm 2014, 3:125
DOI: 10.4172/2167-065X.1000125
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