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Branca Vlaming

Department of Theoretical Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMSS), Amsterdam Center for Multiscale Modeling (ACMM), Vrije Universiteit Amsterdam, The Netherlands
Publications

Spare Receptors and Drug Design Maximizing Therapeutic Benefit

The landscape of drug design is undergoing a transformative shift with the recognition of spare receptors, challenging the traditional paradigm of full receptor occupancy for maximal therapeutic efficacy. Spare receptors, also known as constitutive activity or receptor reserve, represent a reservoir of untapped potential in drug development. This a... Read More»

Branca Vlaming

: J Cell Mol Pharmacol 2023, 7:175

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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