ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
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Citations : 1529

Journal of Infectious Diseases & Therapy received 1529 citations as per Google Scholar report

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Bo Liu

China

Publications

Predicting Fluconazole Drug-Drug Interactions Using a Physiologically-based Pharmacokinetic (PBPK) Model

Aim: Physiologically Based Pharmacokinetic (PBPK) model is developed to (1) simulate clinical trials involving the Drug-Drug Interactions (DDI) between fluconazole and drugs (substrates) metabolized primarily by CYP2C9 and CYP3A, and to (2) support dosing recommendations. Methods: The plasma-concentration profiles were simulated in virtual individ... Read More»

Xue Li, Keheng Wu, Zhou Zhou, Ranran Jia, Youni Zhao, Jingxi Li and Bo Liu

: J Infect Dis Ther

10.4172/2332-0877.1000504

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article