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Arwa Tagoug

Institut Pasteur de Tunis, Avenue Jugurtha, Tunis, Tunisie
Publications

Novel RNA Polymerase I Inhibitor CX-5461 Exhibits Antitumor Activity in Multiple Myeloma

rDNA transcription is steadily dysregulated in multiple myeloma, through oncogenes and anti-tumor routes, and particularly by c-Myc. The main downstream goals of c-Myc involve ribosomal biogenesis to enhance the protein translation capacity necessary to support the growth and self-renewal programs of malignancy cells. In the research of therapeutic... Read More»

Arwa Tagoug

: J Oncol Res Treat

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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