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Anthony Gallagher
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Investigating Phenylalanine/Tyrosine Pathway Fluctuations in Alkaptonuria under Nitisinone Treatment
Alkaptonuria is a rare metabolic disorder characterized by the deficiency of homogentisate 1,2-dioxygenase, leading to the accumulation of homogentisic acid (HGA) derived from tyrosine metabolism. Nitisinone, an inhibitor of 4-hydroxyphenylpyruvate dioxygenase, is commonly used in the management of alkaptonuria to reduce the production of HGA. Howe... Read More»
: J Obes Metab 2024, 7:222
10.4172/jomb.1000222Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article
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