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Ion suppression effect of dosing vehicle excipient Cremophor EL (CrEL) on the accuracy of liquid chromatography/ tandem mass spectrometry (LC-MS/MS) measurements was studied. Ion suppression cause significant errors in accuracy of the measured concentrations of test compounds, thereby invalidating the assessment of pharmacokinetic results. Using Cr... Read More»
Vijaya Bhaskar V, Anil Middha, Sudhir Tiwari and Savithiri Shivakumar
Research Article: J Anal Bioanal Tech 2013, 4:167
DOI: 10.4172/2155-9872.1000167
Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article
Vijaya Bhaskar V, Anil Middha, Sudhir Tiwari and Savithiri Shivakumar
Research Article: J Anal Bioanal Tech 2013, 4:166
Determination of Cremophor EL in Rat Plasma by LC-MS/MS: Application to a Pharmacokinetic Study
Vijaya Bhaskar V, Anil Middha, Sudhir Tiwari and Savithiri Shivakumar
Research Article: J Anal Bioanal Tech 2013, 4:163
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