Figure 6: Summary diagram of signaling pathways modulated by CXCL13:CXCR5 interactions. CXCL13 binding to CXCR5 results in the activation of PI3K/Akt, Raf/MEK/ERK, Integrin-�3/Src/FAK, and DOCK2/Rac/ JNK pathways involved in cell survival, invasion, and growth respectively.