Figure 1: Sepsis increased renal 4-HNE protein adduction. Representative 4-HNE western blot from mice subjected to CLP (sepsis) or sham surgery. Actin was used as a loading control. Densitometry showing band intensity 4-HNE/actin. Mice subjected to CLP (18 hr) showed increased 4-HNE compared to sham animals. *P<0.05 vs. sham; n = 4/group.