Figure 1: Alefacept-mediated selective killing of memory CD2hi CD4+ T cells harboring HIV genome via engagement of CD2 on T cells and CD16 (FcR) on NK cells but not CD2lo CD4+ T cells (Uninfected or naïve cells). ADCC: Antibody Dependent Cellular Cytotoxicity; FcR: Fc Receptor (CD16); LFA-3: Lymphocyte Function-Associated Antigen 3