| Neuronal pathways, classical neurotransmitters and neuropeptides involved
in the hippocampus in major depression. 5-HT: serotonin; Ach: acetylcholine;
DA: dopamine; GABA: gamma-aminobutyric acid; Gal: Galanin; Glu: glutamate;
NPY: neuropeptide Y; SP: substance P; 5-HT2A: the 5-HT2A subreceptor of
the serotonergic receptor; 5-HT7: the 5-HT7 subreceptor of the serotonergic
receptor; alpha4 beta2 nAch: the alpha4 beta2 nAch receptor of the nicotinic
cholinergic subreceptor; D2: the D2 subreceptor of the dopaminergic receptor;
GABAA: the GABAA subreceptor of the GABAergic receptor; Gal2: the Gal2
subreceptor of the galanin receptor; NK1: the NK1 subreceptor of the tachykinin
receptor; NMDA: the N-methyl-D-aspartate subreceptor of the ionotropic
glutaminergic receptor; NPY1: the NPY1 subreceptor of the neuropeptide Y
receptor; A plus mark indicates a postsynaptic excitatory impulse; a minus mark
indicates a presynaptic inhibitory impulse. |
