Figure 6: Amino acid Sequence of the Human GLP-1R. The signal peptide is highlighted in red circles (1-23). Residues in yellow highlight conserved cysteine residues that form disulphide bonds. Residues in blue show amino acid important in agonist binding. Amino acids that have a structural role are highlighted in orange. Glycosylation sites are shown in grey. Residues important in receptor internalization are shown in purple and for activation and functions are in green. |