Figure 3: The Pasteur-Warburg frame. The Pasteur effect is defined by the inhibition of fermentation by oxygen. During the Warburg effect, oxygen bubbles within a mitochondrion are supposed to lead to a mitochondrial dysfunction, and therefore to enhance the aerobic glycolysis and the pentose phosphate pathway. Note that both mitochondria contain the same amount of oxygen particles. Cell divisions are expected to restore a normal oxidative phosphorylation |