Figure 4: Elucidatating the mechanism of action of Larazotide acetate in preventing intestinal permeability. Larazotide acetate is a intestinal tight junction regulator peptide that prevents the opening of intestinal epithelial tight junctions and prevents the crossing of immunogenic gluten peptides across the intestinal barrier and prohibits the onset of disease pathogenesis at initial stages. This could be considered as an efficient strategy in managing Celiac Disease.