Figure 4: PDGF-AA and BDNF influence NPC differentiation. The ability for PDGF-AA and BDNF to induce NPC differentiation was assessed after 3 days (A) and 4 days (B) of treatment by RT-qPCR against PDGFRa and Olig 1 (oligo-lineage) and B3-Tub (neuronal lineage) markers. All data is presented as normalized mRNA levels against the endogenous control b-actin. *significance, p<.05.