Figure 1: Average RFI values and cell viability with each peeling agent. The RFI values for CD86 and CD54 expression on THP-1 cells were measured after exposure to the peeling agent. We defined the agent as a sensitizer if either the RFI of CD86 was equal to or more than 150% or the RFI of CD54 was equal to or more than 200%. It was defined as a non-sensitizer if both RFIs of CD86 and CD54 were below the criterion. The results are shown as means ± SD from three independent experiments with (A) LA, (B) GA, (C) TCA, (D) SA, and (E) phenol. ●=CD86; ■=CD54; ▲=Viability. Red dotted line=criterion for CD86 positivity; blue dotted line: criterion for CD54 positivity.