*indicates a significant difference from the corresponding value at 3 months of age within the same strain and
†indicates a significant difference from the corresponding value in GK rats
Figure 1: Time course measurements of blood glucose levels (Panel A) and urinary protein excretion (Panel B) in Goto-Kakizaki (GK) rats and the modified GK substrain susceptible to diabetic nephropathy (T2DN) rats during 3 to 18 months of age. Numbers in parentheses indicate the number of rats studied per group per time period. Values are means ± S.E.