Figure 1: Overview of type 2 diabetes mellitus (T2DM). a) Carbohydrates, metabolized to glucose in digestive tract, are released into blood stream b) stimulating the pancreas to produces insulin c). With insulin resistance, either the production of insulin decreases or it cannot bind to its receptor, d) resulting in decrease in uptake of glucose by organs likes muscles. This ultimately results in increased blood glucose levels increases and end in the development of T2DM. |