Figure 3: HIV-1 gp120 flexibility and predicted B-cell immunogenicity.
Here the structure of gp120 containing an intact V3 loop (PDBID: 2B4C) is shown in cartoon representations coloured by heat gradient (blue = least, red = most), according to either its crystallographic b-value -a measure of flexibility (left), or to its predicted b-cell immunogenicity by the BEprot server (right). The two representations are oriented to fully display the CD4bs, which has been circled in yellow. |