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Chronic Daily Headache (CDH) and Medication overuse headaches (MOH) are important public health problems. CDH is defined as a headache occurring on 15 days or more per month over three month duration with a worldwide prevalence of 4%. MOH is a daily or near daily headache over 15 days a month that results from overuse of migrain.. Read More
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New daily persistent headache (NDPH) is defined as a persistent and daily headache from onset. It is a unique headache that typically seen in people without a prior history of headaches. New daily persistent headache (NDPH) is an often medication-refractory headache disorder, currently classified as a primary headache disorder. .. Read More
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Bath-Related Headache-The Second Case in South America
Bath-related headache (BRH) is a rare headache disorder described initially by Negoro et al. It is characterized by developing while the patient is bathing in hot water or immersion in a hot bath. We report a case a 63-year-old Brazilian woman who presented several episodes of intense throbbing headache that developed during a h.. Read More
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Background: Chronic, axial lower back pain is most commonly caused by either inflammation of the lumbar facet joints or arthritic changes at the joints. Chronic low back pain is the number one cause of missed work and disability in the working population. The scientific literature demonstrates that when the medial branches are t.. Read More
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Background: Multiple nerve blocks (MNB) provide excellent time-limited perioperative analgesia following total knee arthroplasty. Both perineural and systemic use of dexamethasone (DXM) as an adjuvant to local anesthetic prolong the duration of single-shot MNB. We hypothesized that preoperative perineural injection of DXM prolon.. Read More
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Objective: The aim of this work is to compare between thoracic epidural anesthesia (TEA) and segmental thoracic spinal anesthesia (TSA) conducted for breast surgeries as regard to hemodynamic changes (blood pressure, heart rate, oxygen saturation, ETCO2), postoperative pain control, postoperative analgesic requirements, surgeon .. Read More
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Pre-Trigeminal Neuralgia Similar to Atypical Odontalgia: A Case Report
A 68-year-old man underwent extraction of a left mandibular third molar and the mesial root of the left mandibular first molar by a dentist in November 2014 after suddenly developing toothache. In May 2015, he visited our clinic complaining of episodes of persistent pain in the left mandibular first molar, but could not give a c.. Read More
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Background: Physical inactivity and intensive sports activity have been found to be associated with LBP. The aim of this study is the presents the data about the prevalence of LBP in young adults and its associations with vitality, physical activity and emotions. We also studied the impact of low back pain on daily activity. The.. Read More
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Introduction: Pain affects the quality of life in cancer patients. The World Health Organization established a simple three-step “ladder” approach in 1986, beginning with nonopioid drugs and progressing to stronger opioids as necessary. The implementation of this guideline enables analgesia to be achieved in 75% to 9.. Read More
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Are Platelet Rich Plasma Injections More Effective in Tendinopathy or Enthesopathy?
Introduction: Chronic overuse insertional tendinopathy (entesopathy) is highly prevalent, but is an extremely difficult condition that generates a high medical expense. Alternative and co-adjuvant therapies to improve the quality of life and physical function of affected patients are currently being sought. Materials and Method.. Read More
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Acupuncture or dry needling, in clinical practice have been used successfully in the treatment of pain associated with muscle tone alterations. However a possible direct effect on muscle tone has never been clearly separated from its analgesic action. The H-reflex is a recognised neurophysiological index of the excitability of s.. Read More
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Headache Attributed to Airplane Travel in a Child-First Case in Brazil
Headache attributed to airplane travel (HAAT) is a rare form of headache disorder that develops exclusively during plane travel. HAAT is characterized by occurring during takeoff or landing or both and improves spontaneously within 30 minutes after the ascent or descent of the airplane is completed. We report the case of a 9- ye.. Read More
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The Chronic Low Back Pain Epidemic in Older Adults in America
Chronic low back pain is a debilitating condition affecting millions of Americans annually. Older-adult populations suffer a high prevalence of this continually painful state, and further face a unique set of challenges to manage short- and long-term biopsychosocial functioning. As the population ages, and the proportion of olde.. Read More
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We herewith describe a topical formulation of phenytoin with a clear analgesic effect in localized neuropathic pain: in post herpetic neuralgia and trigeminal neuralgia. Such topical analgesic effect for phenytoin has not yet been described in literature. We have developed various topical phenytoin formulations and identified a .. Read More
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Ketamine-The Confluence of Old and Recent Concepts
Not many drugs in anaesthesiology have gained so much attention as ketamine got for so many years. It has been used worldwide for the last five decades through various routes and for various indications. In its early year of its manufacture, it was considered a wonder or magic drug though the popularity declined with observation.. Read More
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Music is Medicine: Exploring the Use of Melody as an Adjuvant to Regional Anesthesia in Obstetrics
Music has been employed in anesthesiology to alleviate anxiety in patients before, during and after surgery to minimizes or eliminates the need for sedatives. Obstetric anesthesiology utilizes mainly regional techniques and can present a special challenge to the anesthesiologist because the patient is awake and exposed to multip.. Read More
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Background: This subgroup analysis of a prospective, non-interventional study involving general practitioners/ internists evaluated tapentadol prolonged release (PR) in patients who previously received oxycodone/naloxone. Methods: This non-interventional study, which had a 3-month observation period, included 5002 patients. Dat.. Read More
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In extreme cases Methadone has been used for severe pain in oncologic patients; frequently cancer patients have severe headaches in addition to their pain. This patient is a 50 year old Hispanic female with metastatic Burkitt’s Lymphoma and controlled HIV on triple therapy. Throughout her inpatient hospitalizations of chem.. Read More
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Bimoclomol and arimoclomol are small new chemical entities which have been synthesized during the end of last century by a Hungarian pharmaceutical company, Biorex. Both compounds consistently increase Heat Shock Protein (HSP) expression and reduce functional as well as structural pathology in a series of animal models. The deve.. Read More
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Alport Syndrome results in a genetic mutation in type IV collagen; one place of major significance is the glomerular basement membrane of nephrons. These patients are at high risk for glomerulonephritis and renal failure in addition to inner ear and eye pathology. This patient is a 25 year old Caucasian female with non-deaf Alpo.. Read More
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