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Once thought to be a concern of developed nations, low- and middle-income countries are now witnessing a rapid rise in overweight and obesity. Among children of 5-19 years, a huge leap in the prevalence of overweight and obesity was observed during the last 4 decades. Obese children are at increased risk of cardiometabolic morbi.. Read More
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Background: Mediterranean and vegan diets improve body weight and gut microbiome composition. The aim of this study was to compare both diets head-to-head. Methods: Randomized cross-over trial, conducted February-October 2019. Sixty-two overweight adults were assigned to each diet for 16-week periods in random order, separated .. Read More
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Factors Influencing Weight Loss after Bariatric Surgery: A Multivariate Analysis
Introduction: Obesity is a major public health concern due to its association with the development of obesityrelated comorbidities. The aim of this study is to identify the potential relationship between pre-operative patient-related factors with weight loss at 1 and 3 years following Laparoscopic Roux-en-Y gastric bypass (LRYGB.. Read More
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Introduction & Objective: The growing epidemic of obesity is a leading cause of morbidity and is associated with dysfunction across multiple organ systems. Bariatric surgery may result in significant and sustained weight loss along with potential improvement of obesity-related comorbidities, including genitourinary dysfuncti.. Read More
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A Review on Congenital Leptin Deficiency: Phenotypes, Diagnosis and Management
Obesity commonly occurs as a result of environmental polygenic factors but it can be caused by a number of nonenvironmental non-polygenic conditions, the so called monogenic forms of obesity, which are rare causes of obesity, the treatable form of which is congenital leptin deficiency which is a clinical condition that.. Read More
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Background and Aims: The present study investigates the effect of 4-h time restricted feeding on body weight, leptin concentration and lipid profile in healthy non-obese male Wistar rats.Methods and Results: Rats placed on time-restricted feeding (TRF) regimen had freely access to food for 4 hour per day at designated .. Read More
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Objective: The objective of this paper is to present data on participant recruitment, retention, and weight loss success during a psychophysiological study in women with obesity. Methods: Volunteers were women with obesity, 20 – 45 yr, with a BMI between 30 – 45 kg/m2. The study was approximately 20 weeks in duratio.. Read More
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Demystifying the Obesity Paradox in Acute Conditions and Injuries
Efficient lipid storage has been crucial to survival for much of human history; however, in the modern era, this trait has evolved into a rising obesity pandemic of great concern, with rates tripling since 1975. Obesity is a well-established pro-inflammatory process leading to diabetes, hypertension, heart disease, cancer, and o.. Read More
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Background: Zanthoxylum piperitum (ZP) is a spice that is widely used in Asia. It is uniquely flavored and creates a tingling sensation in the mouth and tongue. An anti-obesity effect from ZP has been reported, but the mechanism is not well understood. Objective: To evaluate the effects of ZP on adiposity. Methods: Fresh fruit.. Read More
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10 Years Follow-Up after Bariatric Surgery: Body Composition, Weight and Diabetes
Introduction: Obese patients have better glycemic control and/or Type 2 diabetes mellitus (T2DM) remission after bariatric surgery. Objectives: To evaluate body composition in obese patients after Roux-en-Y Gastric Bypass surgery (RYGB). Methods: Anthropometric measurements, subcutaneous adipose tissue (SAT) and muscle thickne.. Read More
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Achalasia after Sleeve Gastrectomy: A Surgical Challenge
The prevalence of achalasia in the morbid obesity population is low. However, there havebeen cases of patients diagnosed with both conditions, including some diagnosed with achalasia after undergoing bariatric surgery. Even though the surgical management of both conditions has been well studied separately, there is no consensus .. Read More
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Roux en Y Gastric Bypass after Failed Primary Restrictive Procedures in Morbidly Obese Patients
Background: Worldwide prevalent over the past several decades, Obesity morbidities and health related adverse effects has been an increasing concern that lead to revolutionary advancements in the field of bariatric surgery. The long-term outcomes of the different techniques in have gained popularity in the last years. Although s.. Read More
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In our opinion there is a shortage of scientific reports on correlations between WHtR and serum lipid levels in elderly in postmenopausal women. The PubMed search results only in merely one study focused on WHtR variability as a function of serum lipid levels, total cholesterol (TC), triglycerides (TG), and high-density choleste.. Read More
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Is Gestational Weight Loss Safe for Obese Women?
Obesity, defined as having a body mass index (BMI) greater than or equal to 30 kg/m2, is a global epidemic affecting an estimated 650 million people. The risks related to obesity at the start of pregnancy are substantial and may affect the health of mothers and their offspring child, both short- and long-term. Although there is .. Read More
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Background: With the westernization of lifestyle, sub-Saharan Africa is facing a double burden of malnutrition with the coexistence of overnutrition and undernutrition. There is a lack of data among youth who represent a target population for early intervention. The objective of this study was to estimate the prevalence and fact.. Read More
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The BMI Bias: The Validity Problems of Using Self-Reported Data to Measure Body Mass Index
Obesity has been increasing at an alarming rate over the past several years, affecting countries of every development status. The burden of obesity is largely carried by those of low income and this is a shift from previous periods in time. In order to adequately design effective health policies, there is a need for accurate mea.. Read More
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About Non-infectious Scrotal Elephantiasis: 5 Cases with Management Algorithm
Introduction: Despite the fact that massive scrotal elephantiasis is relatively uncommon in the Western world, the diagnostic and therapeutic know-how is highly important, since the condition has a huge impact on the patients’ quality of life. In endemic territories it is usually an infection that leads to this chronic, be.. Read More
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Assessment of Enteral Nutrition Product Support and Quality of Life in Underweight Young Adults
Introduction: Nutrition is important to prevent diseases caused by insufficient nutrition and favors quality of life by enhancing functionality. Nutrition and diet were considered as components of quality of life definition in the past. Objective: In this study, we aimed to assess effects of enteral product support on quality o.. Read More
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Objective: Sleeve gastrectomy (SG) is an established bariatric surgical procedure in the United States yet patient attributes that influence outcomes following SG remain inconclusive. Therefore, identifying baseline variables that predict weight loss (WL) success at one and two-year follow-up was investigated. Methods: Retrospe.. Read More
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Introduction: About 25% of patients suffering end stage heart failure (ESHF) are obese. BMI>40 prevents patients from receiving an organ graft because morbid obesity (MO) dramatically increases mortality after heart transplantation (HTx). Moreover, MO (BMI>40) increases the risk of thromboembolic events by 20%. The treatme.. Read More
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