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Epidemiological Status of Visceral Leishmaniasis in Iran: Experiences and Review of Literature
Abstract Background: The Mediterranean form of visceral leishmaniasis (VL), or kala-azar, is a potentially fatal vector-borne zoonotic disease. At the present time, VL caused by Leishmania infantum is recognized as an important parasitic disease in Iran. Objective: The aim of the study was to review the epidemiological aspect.. Read More
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Sub-Saharan countries are facing a demographic growth of 3% per year. That increase of the population in number, associated with climate changes, has deeply modified environmental landscape and affected biodiversity. The distribution of tsetse flies or Glossina, vector of sleeping sickness, has been considerably modified over ti.. Read More
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Aims and objectives:The aims of the present study were to introduce a novel modality for estimation of the anti-neoplastic efficacy of chemotherapeutic agents and to compare this technique with one of the most widely used techniques, the DNA fragmentation assay. Methods:Squamous cell carcinoma cell line HEp-2 w.. Read More
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Background: Chronic or binge ethanol exposures during development can cause fetal alcohol spectrum disorder (FASD) which consists of an array of neurobehavioral deficits, together with structural, molecular, biochemical, and neurotransmitter abnormalities in the brain. Previous studies showed that perinatal neurodevelo.. Read More
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Introduction: B lymphocyte, macrophage and mast cell densities in the stroma underlying cervical low and high grade squamous intraepithelial lesions (LSIL and HSIL) and squamous cell carcinoma (SCC) in 200 tissue samples, with concomitant HPV typing, was assessed, in order to examine their relationship to disease status and prog.. Read More
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Dirofilaria immitis is the causal agent of heartworm diseases and of human pulmonary dirofilariosis. The infection is transmitted by several species of culicid mosquitoes that are frequently able to bite both animal reservoirs and humans. Canary Islands (Spain) constitute a well documented endemic area of canine dirofilariosis.. Read More
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FUS1, also known as tumor suppressor candidate 2 (TUSC2), is a novel candidate tumor suppressor gene (TSG) frequently inactivated in human lung cancer. Loss of FUS1 protein expression is found in almost all small cell lung cancer (SCLC) cell lines and tumor specimens. Therefore, restoration of normal FUS1 function by gene tra.. Read More
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Physiological Bases in Definition of Leukocyturia and Erythrocyturia
Background: In amount of leukocyturia and erythrocyturia has been used to diagnose renal diseases for a long time. In addition the mentioned features are the ones among principal criteria to identify urinary syndrome. The aim of the research work was to define such the proper physiological regimen of kidneys functioning workin.. Read More
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Parathyromatosis Coexisting with Papillary Thyroid Microcarcinoma
Summary: The aim of this report is to describe a fortuitely discovered association between parathyromatosis and papillary thyroid microcarcinoma. Case description: A 56 year old woman presented with a pyelic relapsed stone, bone pains, neurovegetative complaints and iPTH = 348 ng/l as manifestations of recurrent primary hyperp.. Read More
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One-Stage Model of Experimental Myocardial Infarction in Rats
Background: In recent years, due to technical and economic considerations much of the experimental work is carried out on small laboratory animals such as mice and rats. In addition, researchers have to use mainly one-stage methods of MI modeling, which rely on vessel ligation. Objective: The aim of the study was to create a s.. Read More
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Race and Triple Negative Breast Cancer
Breast cancer is understood to represent not a single disease but a heterogeneous group of tumors with different biologic behavior, prognosis and response to treatment. Luminal A, luminal B, HER2 overexpressing, triple negative and basal subtypes of breast carcinomas are now considered distinct entities with unique biologic ch.. Read More
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