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Indication Criteria of Imaging Exams for Diagnosing of Temporomandibular Joint Disorders
The various subtypes of temporomandibular disorders and different imaging exams available for diagnosis and indication influence the choice of the most appropriate examination front of clinical symptoms of the patient. This review aims to provide an indication of imaging tests for the diagnosis of pathological changes of the tem.. Read More
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Glomus tumors are uncommon lesions that may even occur in the gastrointestinal tract. We collected 6 cases of glomus tumors (5 females, 1 male) with a median age of 65.5 years (range 48-86 years) arising from stomach (5 cases) and colon. The tumor sizes varied from 1.5 to 3.5 cm (median 2.5 cm). In our Institutions, the frequenc.. Read More
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A Case of Recurrent Basal Cell Carcinoma Diagnosed on Fine Needle Aspiration Cytology
Basal Cell Carcinoma (BCC) is the most common malignant skin tumor. Its diagnosis is made on clinical grounds followed by confirmation on histopathology. Fine Needle Aspiration Cytology (FNAC) can be reliably used to evaluate skin tumors especially BCC. Here a case of recurrent BCC of skin successfully diagnosed through FNAC is .. Read More
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Background: The Centers for Medicaid and Medicare Services approved a number of panels as screening tests including those for liver functions. The utility of routinely testing for Aspartate aminotransferase (AST) and direct bilirubin was questioned and empirical data analyzed to suggest alternatives. Methods: Tests done over s.. Read More
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Background: We have previously demonstrated that brain levels of gamma-aminobutyric acid (GABA) were diminished in patients with various types of dysgeusia and dysosmia by use of magnetic resonance spectroscopy (MRS). We also demonstrated by use of functional magnetic resonance imaging (fMRI) of brain that when these patients we.. Read More
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Mesenchymal Stem Cell Applications for Ligament Repair after Joint Trauma
Tendon and ligament injuries are the most common problems in adult health accounting for about half of all musculoskeletal injuries. Rupture of the anterior cruciate ligament (ACL) results in the loss of whole joint stability leading to meniscal rupture, cartilage damage and early osteoarthritis. Arthroscopic reconstruction usin.. Read More
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Background: This study aimed to establish a standard gene analysis procedure for successful mutation analysis in pathology laboratories using formalin-fixed paraffin-embedded gastrointestinal stromal tumor (GIST) specimens. Methods: Twenty-six cases of GIST were retrospectively collected and subjected to polymerase chain reacti.. Read More
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Aqueous and methanol leaf extracts of V. sinaiticum were investigated for the presence of secondary metabolites and their in vitro activity against Trypanosoma congolence, the main causative agent of African animal trypanosomosis in Sub-Saharan Africa and Ethiopia. The in vitro assay was carried out by monitoring test concentrat.. Read More
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Confocal laser endomicroscopy (CLE) is a novel microscope which enables real-time imaging with detailed mucosal and sub mucosal architectures throughout the gastrointestinal tract. New optical technology using the principle of light reflection, scattering and refocusing dramatically increases image resolution thus has the potent.. Read More
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ERK5 Silencing Inhibits Invasion of Human Osteosarcoma Cell via Modulating the Slug/MMP-9 Pathway
Background and aim: ERK5 is over expressed in a many of human cancers and this overexpression has been associated with metastasis and invasion. Furthermore, ERK5 siliencing inhibits aggressive phenotypes of cancer cells. However, mechanisms by which ERK5 regulates tumour progression or metastasis have not been elucidated. In thi.. Read More
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The aim of the study was to evaluate the polioencephalomalacia induced with amprolium in goats: pathologic changes of the central nervous system. Eight apparently healthy goats of 6 to 9 weeks of age were drenched with amprolium (200 mg/kg body weight) till the development of clinical signs. Three goats of the same age group wer.. Read More
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Improved Method for Estimating M-Spike Proteins in Serum Protein Electrophoresis
Context: Serum monoclonal immunoglobulin (M-spike) in multiple myeloma is measured by gel electrophoresis (SPE) followed by densitometric scanning of the gel. The current standard methods delimit the M-spike component based on the projected gel image on screen (current standard method, CSM). However, the M-spike could also be se.. Read More
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We compared the survival of women diagnosed with invasive lobular carcinoma subtypes prior to and during the mammography screening era to determine the impact of early detection and treatment in an early phase upon survival according to tumor subtypes. Using mammographic tumor features, we classified 428 consecutive invasive lob.. Read More
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Could Neutrophil Extracellular Traps Elucidate the Mysteries of Pathogenesis?
Recently, NETosis emerged as a specific type of neutrophil death that is involved in innate immunity, and its products ‘’Neutrophil extracellular traps (NETs)’’ are now implicated as new candidates in a diversity of pathologic states. NET formation in contact to different pathogens or a variety of stimuli.. Read More
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The Prognostic Influence of CD44 in Oral Squamous Cell Carcinoma
Oral Squamous Cell Carcinoma (OSCC) is the most frequent malignant tumor of the oral cavity, exhibiting a heterogeneous behavior. Because the mortality rate for this tumor has essentially remained unchanged over the last few decades, the need exists for more reliable prognostic factors in OSCC. The objective of this review was t.. Read More
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Immunohistochemical Analysis of mTOR Pathway Expression in Gastric Neuroendocrine Tumors
Background: The mammalian target of rapamycin (mTOR) is an important regulator of cell proliferation and protein translation and is activated in various malignancies. Expression of mTOR cascade components in gastric neuroendocrine tumors (NETs), however, has not yet been fully explored. Aims: The goal of the present study was .. Read More
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Introduction: Thyroid nodules are among the most common endocrine complaints in the United States. With increasing incidence of differentiated thyroid carcinoma there has been a widespread interest in development of minimally invasive treatments such as percutaneous ethanol injection (PEI) to manage thyroid pathology. In our rev.. Read More
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Background: Angiosarcomas (AS) are high-grade sarcomas that comprise less than 1% of soft tissue sarcomas. We compared clinical, pathological and molecular features of primary and recurrent conventional AS, including cases occurring in unusual backgrounds, such as organ transplants, at a site of metal orthopedic implant, and at .. Read More
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Pkd-Tsc Syndrome and Renal Cell Carcinoma: A Case Report
Introduction: In this work we report a clinical case of PKD-TSC syndrome, with a review of current literature. Case report: In August 2013 we admitted in our clinic a patient with an history of Tuberous Sclerosis Complex (TSC) who had a CT finding of right renal tumor in a kidney with multiple cists. After performing a right ra.. Read More
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Accuracy of Combined Tru Cut and FNAC in Preoperative Sampling of Ovarian Tumors
Background: Preoperative histologic confirmation of malignant ovarian tumors before chemotherapy is mandatory. There are few reports about combined use of tru cut and FNAC as methods of preoperative sampling of ovarian tumors. Patients and methods: This is a prospective study conducted on 50 female patients presented with adva.. Read More
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