Make the best use of Researched information from 700+ peer reviewed, Open Access Journals operated by 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on Medical, Pharma, Engineering, Science, Technology and Business
Introduction: Even though surgical intervention is the preferred option in treatment of Bisphosphonate-related Osteonecrosis of the Jaws (BRONJ) the application of low-level-laser therapy (LLLT) has been described either as part of conservative protocols or as adjuvant measure in surgical regimes. So far there are no reports con.. Read More
To read the full article Visit Full Article | Download Full Article
Background and objective: Gliomas remain the most common and problematic primary brain tumors to treat given their mobile and invasive characteristics, resulting in a 5 years survival rate of less than 5%. Recently the administration of photosensitive fluorescent drugs has been utilized to aid in the identification and resection.. Read More
To read the full article Visit Full Article | Download Full Article
An Electron Transferred Alkaloid Mixture Composed for Until Now Incurable Hepatitis B
The ideas to start investigate protoberberines curable influence to infected patients is based on the fact that certain African tribe uses Enantia chlorantha species. The multiple electron transfer of natural bis-benzyl-isoquinoline alkaloid (protoberberine) mixture was successfully to recover hepatitis B. Therefore we deci.. Read More
To read the full article Visit Full Article | Download Full Article
Tenofovir (TNF) and emtricitabine (FTC) are both reverse transcriptase inhibitors, often used in combination for anti-retroviral therapy. In the present study, a reverse phase high performance liquid chromatographic method was developed and validated for the simultaneous estimation of TNF and FTC in human plasma using stavudine .. Read More
To read the full article Visit Full Article | Download Full Article
Detection of Soluble Oligomers Formed by PB1-F2 Influenza A Virus Protein in vitro
Influenza A viruses (IAV) remain a major cause of respiratory disease worldwide each year and have been responsible for three main pandemics during the last century comprising the Spanish flu which killed up to 50 million of people. IAV are RNA enveloped viruses belonging to the Orthomyxoviridae family. The nature of the genome .. Read More
To read the full article Visit Full Article | Download Full Article
Selecting the “right” monoclonal antibody (mAb) for an immunoaffinity-based application can be tricky, as many mAb producers offer a wide range of mAb clones against molecular structures of interest. Since there are significant differences in the quality of mAb clones, and particularly in their binding activity,.. Read More
To read the full article Visit Full Article | Download Full Article
Ion suppression effect of dosing vehicle excipient Cremophor EL (CrEL) on the accuracy of liquid chromatography/ tandem mass spectrometry (LC-MS/MS) measurements was studied. Ion suppression cause significant errors in accuracy of the measured concentrations of test compounds, thereby invalidating the assessment of pharmacokinet.. Read More
To read the full article Visit Full Article | Download Full Article
Why Not Introducing the Third Dimension in Photodynamic Therapy Research?
Photodynamic therapy (PDT) is a clinically approved procedure for the treatment of diseases characterized by uncontrolled cell proliferation, particularly cancer. It involves the administration of a photosensitizer (PS) that is able to produce reactive oxygen species (ROS) upon irradiation with light, leading to the selective ki.. Read More
To read the full article Visit Full Article | Download Full Article
For the fundamental study of photodynamic therapy, protein-damaging activity of the water-soluble phosphorus(V) porphyrin (DDP(V)TPP) was examined. Absorption spectrum measurement demonstrated the binding interaction between DDP(V)TPP and human serum albumin, a water-soluble protein. Photo-irradiated DDP(V)TPP damaged the amino .. Read More
To read the full article Visit Full Article | Download Full Article
A simple spectrophotometric method based-uricase enzyme for the detection of uric acid in normal urine and gout patient’s urine samples has been developed based on the reaction of hydrogen peroxide (H2O2) with yellow color of 4-Aminodiphenylamine Diazonium Sulfate (variamine blue RT salt) to yield a pale yellow-green colou.. Read More
To read the full article Visit Full Article | Download Full Article
Ion suppression effect of dosing vehicle excipient Solutol HS15 (SHS15) on the accuracy of liquid chromatography/ tandem mass spectrometry (LC-MS/MS) measurements was studied. Ion supression cause significant errors in accuracy of the measured concentrations of test compounds, thereby invalidating the assessment of pharmacokinet.. Read More
To read the full article Visit Full Article | Download Full Article
Determination of Cremophor EL in Rat Plasma by LC-MS/MS: Application to a Pharmacokinetic Study
A rapid sensitive, and selective pseudo MRM based method for the determination of Cremophor EL (CrEL) in rat plasma was developed using Liquid chromatography/Tandem mass spectrometry (LC-MS/MS). The analytes were detected using atmospheric pressure chemical ionization (APCI) tandem mass spectrometry. Plasma concentrations of CrE.. Read More
To read the full article Visit Full Article | Download Full Article
Current Trends in Ubiquitous Biosensing
Biosensing technology is not currently capable of widespread use outside of a laboratory environment due to significantly limitation in bioreceptor function and production, as well as in the overall size, weight, and cost of the sensing platform. However, as technology continues to advance, biosensors could truly become ubiquito.. Read More
To read the full article Visit Full Article | Download Full Article
Biosensors are versatile tools for monitoring molecular interactions. Herein, we report a novel assay designed to detect anti-platelet-derived growth factor receptor α (PDGFRα) autoantibodies in the serum of patients affected by systemic sclerosis (SSc), an autoimmune disease of the connective tissue. The assay was b.. Read More
To read the full article Visit Full Article | Download Full Article
New Direct Competition Free but Not Label Free Immunosensor Method for IgG Determination
In the present study, to reduce the excessively long time required for each “competition” measurement performed using the customary competitive immunosensors, an innovative “direct”, i.e. competition free, immunosensor method for IgG determination, was developed. Unlike what is usually reported in the lit.. Read More
To read the full article Visit Full Article | Download Full Article
Immobilization of P22 Bacteriophage Tailspike Protein on Si Surface for Optimized Salmonella Capture
Bacteriophage based technology has gained interest in developing pathogen detection platforms for biosensing applications. In this study, P22 phage tail spike proteins (TSPs) have been immobilized on Si surfaces for optimized capture of host Salmonella enteric serovar Typhimurium. It was then demonstrated that roughening of the .. Read More
To read the full article Visit Full Article | Download Full Article
The detection and evaluation of concentration of influenza virus proteins in biological samples is critical in a broad range of medical and biological investigations regarding the concern over potential outbreaks of virulent influenza strains in animals and humans. This paper describes a sensitive, label-free approach for the de.. Read More
To read the full article Visit Full Article | Download Full Article
Electrochemical Nanosized Biosensors: Perspectives and Future of Biocatalysts
Electrochemical biological sensor device unite the sensitivity of classic instrumental techniques with the inseparable selectivity of the biological agent. The bio-element of the sensing device identifies the analyte following in a biocatalytic way and definitely generates an electrical response recorded by a transducing element.. Read More
To read the full article Visit Full Article | Download Full Article
A new biosensor composed of 1-butyl-3-methylimidazolium hexafluorophosphates (BMIMPF6)-human serum albumin (HSA) film coated on glassy carbon electrode (GCE) was produced. In the current work, the conjugation of ionic liquid (IL) with HSA improved the stability and binding affinity of protein onto GCE. A rapid and reliable volta.. Read More
To read the full article Visit Full Article | Download Full Article
Isolation and Structural Elucidation of Novel Isomeric Process Related Impurities of Zolmitriptan
Four isomeric unknown impurities ranging from 0.08-0.12% were found in the purified sample of Zolmitriptan during the batch analysis by gradient reverse phase ultra performance liquid chromatography (UPLC) and their molecular weights determined by liquid chromatography mass spectroscopy (LC-MS) analysis. Subsequently, all the fo.. Read More
To read the full article Visit Full Article | Download Full Article